Immunobiology of Bacterial CpG-DNA
Bacterial CpG-DNA sequences not only serve for genetic information but act as "danger" signal to alert immune cells such as macrophages and dendritic cells. CpG-DNA directly causes activation of these members of the innate immune system yielding in up-regulation of co-stimulatory molecules...
| Other Authors: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2000, 2000
|
| Edition: | 1st ed. 2000 |
| Series: | Current Topics in Microbiology and Immunology
|
| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- List of Contents
- Mechanism of Action of CpG DNA
- Oligodeoxyribonucleotides with 5’-ACGT-3’ or 5’-TCGA-3’ Sequence Induce Production of Interferons
- Macrophage Activation by Immunostimulatory DNA
- Consequences of Bacterial CpG DNA-Driven Activation of Antigen-Presenting Cells
- Signal Transduction Pathways Activated by CpG-DNA
- CpG DNA Co-Stimulates Antigen-Reactive T Cells
- Role of Type I Interferons in T Cell Activation Induced by CpG DNA
- Hematopoietic Remodeling Triggered by CpG DNA
- CpG DNA Augments the Immunogenicity of Plasmid DNA Vaccines
- The Role of Bacterial DNA in Autoantibody Induction
- CpG DNA in Cancer Immunotherapy
- Use of CpG DNA for Enhancing Specific Immune Responses
- Immunostimulatory-Sequence DNA is an Effective Mucosal Adjuvant
- CpG DNA Switches on Th1 Immunity and Modulates Antigen-Presenting Cell Function
- Effects of CpG DNA on Th1/Th2 Balance in Asthma
- Responses of Human B Cells to DNA and Phosphorothioate Oligodeoxynucleotides