Provisional peer-reviewed toxicity values for trans-Crotonaldehyde (CASRN 123-73-9)

trans-Crotonaldehyde, CASRN 123-73-9, is an α,β-unsaturated aldehyde with defined stereochemistry (WHO, 2008). The commercial product crotonaldehyde is represented by CASRN 4170-30-3 and consists of >95% trans-isomer (CASRN 123-73-9). cis-Crotonaldehyde is represented by CASRN 15798-64-8. trans-C...

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Bibliographic Details
Main Author: Dean, Jeffry L.
Corporate Author: Center for Public Health and Environmental Assessment (U.S.)
Format: eBook
Language:English
Published: Cincinnati, OH Center for Public Health and Environmental Assessment, Office of Research and Development, U.S. Environmental Protection Agency March 2021, 2021
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:trans-Crotonaldehyde, CASRN 123-73-9, is an α,β-unsaturated aldehyde with defined stereochemistry (WHO, 2008). The commercial product crotonaldehyde is represented by CASRN 4170-30-3 and consists of >95% trans-isomer (CASRN 123-73-9). cis-Crotonaldehyde is represented by CASRN 15798-64-8. trans-Crotonaldehyde is primarily used in chemical manufacturing as a precursor, intermediate, or solvent (WHO, 2008; HSDB, 2005). It is synthesized by aldol condensation of acetaldehyde and a dehydration step (HSDB, 2005). Commercial crotonaldehyde and trans-crotonaldehyde are both listed on the U.S. EPA's Toxic Substances Control Act (TSCA) public inventory (U.S. EPA, 2018b), and crotonaldehyde is registered with Europe's Registration, Evaluation, Authorisation and Restriction of Chemicals (REACH) program (ECHA, 2018)
Item Description:"EPA/690/R-21/001F"
Physical Description:1 PDF file (v, 62 pages) illustrations