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Clear Cell Renal Cell Carcinoma 2021-2022

Clear cell renal cell carcinoma is currently one of the most interesting areas of study in oncology. Despite the advances made in this field, this tumor continues to be a health problem of major concern in Western societies, seriously affecting public health services. Several characteristics of this...

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Bibliographic Details
Main Author: Manini, Claudia
Other Authors: López, José I.
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Machine Learning
Prediction Model
Radiomics
Pathway Analysis
Sunitinib
Resistance
Responsiveness
Nivolumab
Transcriptome
T-cells
Prognostic Factor
Angiogenesis
Hypoxia
Renal Cancer
N/a
Architectural Patterns
Inter-tumoral Heterogeneity
Translational
Tumor Microenvironment
Tissue Slice Culture
Diagnosis
First-line Treatment
Disease Progression
Pd1
Magnetic Resonance
Prognostic Factors
Clear Cell Kidney Cancer
Tyrosine Kinase Inhibitors
Clear-cell Renal Cell Carcinoma
Combinations
Metastatic Clear Cell Renal Cell Carcinoma
Epigenetics
Imaging
Plasma
Intra-tumoral Heterogeneity
Thyroid
Immunotherapy
Molecular Features
Inter-metastatic Heterogeneity
Immune Related Adverse Events (iraes)
Pbrm1
Single-cell Rna Sequencing
Ddpcr
Treatment Resistance
Cancer Immunotherapy
Pd-l1
Renal Cell Cancer
Adjuvant Therapy
Clear Cell Renal Cell Carcinoma
Intratumor Heterogeneity
Biomarkers
Circulating Mirna
Dna Methylation
Cystic Tumor
Immune Landscape
Oleic Acid
Immune Checkpoint Inhibitors
Prognosis
Multisite Tumor Sampling
Biomarker
Immune Checkpoint Inhibitor
Kidney
Scd-1
Malignancy
Renal Cell Carcinoma
Pd-1
Surgery
Rna Sequencing
Endothelial Cells
Mirna
Gene Expression
Clinical And Internal Medicine / Bicssc
Immunohistochemistry
Medicine And Nursing / Bicssc
Histomorphological Features
Cutaneous
Radiogenomics
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:Clear cell renal cell carcinoma is currently one of the most interesting areas of study in oncology. Despite the advances made in this field, this tumor continues to be a health problem of major concern in Western societies, seriously affecting public health services. Several characteristics of this tumor make it an exciting meeting point for translational collaboration between clinicians and basic researchers. Clear cell renal cell carcinoma is a paradigmatic example of inter- and intra-tumor heterogeneity from morphological, immunohistochemical, and molecular viewpoints. This tumor is also a good example to investigate the complexity of tumor/tumor and tumor/environment relationships from an ecological perspective. A deeper identification of the varied internal tumor self-organization through the specialization of cell clones and subclones as local invaders and metastasizers, on one hand, and the interactions of specific subsets of tumor cells with the local host microenvironment, on the other, will significantly enrich our knowledge of this neoplasm. Clear cell renal cell carcinoma is also a paradigmatic test bench for antiangiogenic and immune checkpoint blockage therapies. The refinement of these therapeutic tools administered alone or in combination is a hot issue in oncology, and several international trials are underway.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (342 p.)
ISBN:9783036555188
9783036555171
books978-3-0365-5518-8

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