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Nanoparticle-Macrophage Interactions Implications for Nanosafety and Nanomedicine

Nanoparticles (NPs) offer unique properties for biomedical applications, leading to new nanomedicines. Recent examples of advanced nanoparticle-based nanomedicines are COVID-19 RNA vaccines. Regardless of the delivery route of the NPs into the body (intravenous or subcutaneous injection, oral, intra...

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Bibliographic Details
Main Author: Bondarenko, Olesja
Other Authors: Torres Andón, Fernando
Format: eBook
Language:English
Published: MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Icp-ms Analysis Of Cell Bound Sio2
Macrophage
In Vitro Testing
Anti-inflammatory
Inflammation
Gold Nanoparticles
N/a
Protein Corona
Caco-2 Cells
Oral Administration
Monocytes
Bovine Serum Albumin
Nanomaterial
Cell Uptake
Wound Healing
2d Cultures
Zebrafish
Rifabutin
Device
Innate Memory
Carbon Nanotube
Synthetic Amorphous Silica
Phagocytosis
In Vitro Models
Class A Type 1 Scavenger Receptors
Nanostructured Lipid Carriers
Nanomaterials
Nanoparticle
Macrophages
Osteoarthritis
Nr8383 Alveolar Macrophage
Crohn's Disease
Transcriptomics
Nanoparticles
Foot Ulcer
Cytotoxicity
Chronic Wound
Chemokines
Drug Delivery
Immune System
Macrophage-nanoparticle Interaction
3d Cultures
Medicine And Nursing / Bicssc
Multi-walled Carbon Nanotubes
Innate Immunity
Scavenger Receptor
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:Nanoparticles (NPs) offer unique properties for biomedical applications, leading to new nanomedicines. Recent examples of advanced nanoparticle-based nanomedicines are COVID-19 RNA vaccines. Regardless of the delivery route of the NPs into the body (intravenous or subcutaneous injection, oral, intranasal, etc.), NPs inevitably come into contact with immune cells, such as macrophages. Macrophages are phagocytizing cells that determine the fate and the lifetime of NPs in relevant biological fluids or tissues, which has consequences for both nanosafety and nanomedicine. The aim of this Special Issue is to cover recent advancements in our understanding of NP-macrophage interactions, with a focus on in vitro models for nanosafety and novel nanomedicine approaches that allow the modulation of the immunological profile of macrophages. The current Special Issue compiles nine papers: seven research articles and two review articles. The original articles include studies on the interaction of different nanomaterials, such as multi-walled carbon nanotubes (MWCNTs), amorphous silica, gold nanoparticles, lipid carriers, and microspheres, with macrophages in different scenarios.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (208 p.)
ISBN:9783036546001
9783036545998
books978-3-0365-4600-1

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