NTP report on the toxicology and carcinogenicity study of mixtures of 3'-Azido-3'-Deoxythymidine (AZT), lamivudine (3TC), and nevirapine (NVP) (CAS NOs 30516-87-1, 134678-17-4, 129618-40-2) in genetically modified c3B6.129F1-Trp53tm1Brd N12 haploinsufficient mice (In utero and postnatal gavage study)
METHODS: We exposed groups of haploinsufficient C3B6.129F1-Trp53tm1Brd N12 mice by depositing solutions containing AZT, 3TC, NVP, or combinations of the drugs in a methylcellulose solvent directly into the animals' stomachs through a tube twice daily for 28 days following birth; in addition, th...
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| Format: | eBook |
| Language: | English |
| Published: |
Research Triangle Park, NC
National Toxicology Program
October 2013, 2013
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| Series: | NTP GMM
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| Online Access: | |
| Collection: | National Center for Biotechnology Information - Collection details see MPG.ReNa |
Table of Contents:
- Includes bibliographical references