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|a books978-3-0365-2589-1
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|a 9783036525891
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|a 9783036525884
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|a Lupiáñez, José Antonio
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|a Anticancer Properties of Natural and Derivative Products
|h Elektronische Ressource
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|a Basel, Switzerland
|b MDPI - Multidisciplinary Digital Publishing Institute
|c 2021
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|a 1 electronic resource (312 p.)
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|a antioxidant
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|a photosensitiser
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|a actin cytoskeleton
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|a hypericin
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|a extract
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|a natural compounds
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|a caspase-3
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|a cell cycle
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|a Pogostemon cablin (PPa extract)
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|a AKT/PI3K signaling pathway
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|a rhodamine B
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|a n/a
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|a therapeutic triglyceride
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|a glioblastoma (GBM)
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|a DNA
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|a total phenolic content
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|a anti-cancer
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|a 1,3-dipolar cycloaddition
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|a natural extract
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|a 3-hydroxy-β-ionone
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|a lactucopicrin (LCTP)
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|a emodin
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|a total flavonoid content
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|a anti-proliferative activity
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|a antioxidant activity
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|a human hepatocarcinoma HepG2 cells
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|a isolated compounds
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|a interaction
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|a GC-MS
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|a photodynamic therapy
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|a temozolomide (TMZ)
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|a Elaeagnus angustifolia
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|a danthron
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|a lung metastases
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|a cell line
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|a quinizarin
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|a ROS levels
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|a oleanolic acid
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|a chemoprevention
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|a hepatocellular carcinoma (HCC)
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|a click chemistry
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|a anticancer activity
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|a apoptosis
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|a xenograft study
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|a betulinic acid
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|a breast cancer
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|a synergism
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|a complementary medicine
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|a DPPH
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|a betulin glycoconjugates
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|a oral cancer
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|a Caveolin-1
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|a Adenosma bracteosum
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|a NF-κB
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|a cancer
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|a metabolites
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|a uvaol
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|a anti-inflammatory agent
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|a gingival fibroblasts
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|a EMT
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|a wine
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|a melanoma
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|a Moringa oleifera
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|a natural photosensitive compounds
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|a maslinic acid
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|a Olea europaea L.
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|a autophagy
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|a triterpenoic acid
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|a squamous cell carcinoma
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|a anticancer agent
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|a tormentic acid
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|a oxidative stress
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|a in vivo
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|a chemotherapy
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|a cytotoxicity
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|a bioactive compounds
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|a antioxidant enzymes
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|a proliferation
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|a migration activity
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|a medicinal mushrooms
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|a natural product
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|a grapes
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|a p62/SQSM1
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|a Research and information: general / bicssc
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|a ROS level
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|a Pérez-Jiménez, Amalia
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|a Rufino-Palomares, Eva E.
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|a Lupiáñez, José Antonio
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|a eng
|2 ISO 639-2
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|b DOAB
|a Directory of Open Access Books
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|a Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
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|a 10.3390/books978-3-0365-2589-1
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|u https://www.mdpi.com/books/pdfview/book/4698
|7 0
|x Verlag
|3 Volltext
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|u https://directory.doabooks.org/handle/20.500.12854/77079
|z DOAB: description of the publication
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|a 000
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|a 610
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|a 540
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|a 304
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|a 140
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|a Natural products are bioactive compounds synthesized by terrestrial and marine plants, microorganisms and animals, whose main objective is to prevent them from attacks by predators and/or pathogens. Traditionally since ancient times, different cultures have used these compounds for the prevention and treatment of various human diseases. During the last few years, it has been reported that most of these phytochemicals possess a variety of interesting and significant biological properties, such as analgesic, antiallodynic, antidiabetic, antioxidant, antiparasitic, antimicrobial, antiviral, antiatherogenic, anti-inflammatory, antiproliferative, antitumor and normal growth stimulants, as well as significant cardioprotective and neuroprotective activity. This thematic book aims to collect and disseminate some of the most significant and recent contributions of the use of the natural compounds called phytochemicals, as well as some of their chemical derivatives, for the prevention and treatment of cancer and other accompanying diseases. On the other hand, in recent years, the synthesis of numerous chemical derivatives of these natural compounds has also intensified, with the aim of enhancing their bioactive capacities. Among all these bioactivities, special attention has been paid to its antitumor capacity through the potential modulation of cancer initiation and growth, cell differentiation, apoptosis and autophagy, angiogenesis, and metastatic dissemination. In addition, a considerable number of studies have linked their anticancer effects to their anti-inflammatory and antioxidant activities.
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