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008 220822 ||| eng
020 |a 9780645332025 
100 1 |a Sergi, Consolato M 
245 0 0 |a Metastasis  |h Elektronische Ressource 
260 |a Australia  |b Exon Publications  |c 2022 
300 |a 1 electronic resource (198 p.) 
653 |a Molecular Imaging of Brain Metastases; Imaging Tests for the Diagnosis of Lung Nodules; Thoracic Surgery for Lung Cancer; Pulmonary Metastases; Surgery for Pulmonary Metastasis; Metastatic Gynecological Cancers; Epigenetic Changes in Ovarian Cancer Metastasis; Tumor Microenvironment in Ovarian Cancer Metastasis; MetastamiRs; MicroRNAs in Metastatic Prostate Cancer; Hematological Toxicity; Bone Metastasis Radiation Therapy; DNA Damage Response; Cancer Metastasis; Tumor Endothelial Cells in Cancer Metastasis; Apoptosis-Induced Compensatory Proliferation; Targeting Apoptosis to Overcome Chemotherapy Resistance; Metastatic Ewing Sarcoma 
653 |a MJCL / bicssc 
700 1 |a Sergi, Consolato M 
041 0 7 |a eng  |2 ISO 639-2 
989 |b DOAB  |a Directory of Open Access Books 
500 |a Creative Commons (cc), https://creativecommons.org/licenses/by-nc-nd/4.0/ 
024 8 |a 10.36255/exon-publications.metastasis 
856 4 0 |u https://exonpublications.com/index.php/exon/issue/view/metastasis  |7 0  |x Verlag  |3 Volltext 
856 4 2 |u https://directory.doabooks.org/handle/20.500.12854/81846  |z DOAB: description of the publication 
082 0 |a 363 
520 |a Metastasis is the dissemination of neoplastic cells from the primary tumor, and their colonization and growth in another part of the body. The process of metastasis is orchestrated by a complex network of biological events, and our understanding of the processes that regulate metastasis has significantly improved. This open access book provides an in-depth analysis of our understanding of the molecular mechanisms, detection, and clinical management of metastatic cancer. Updates are given on molecular imaging of brain metastasis and recurrence, management of pulmonary nodules for the early diagnosis of lung cancer, surgical management of both primary and metastatic lung cancers, genomic landscapes and tumor evolution of metastatic gynecological cancers, epigenetic changes in metastatic ovarian cancer, microRNAs in metastasis of prostate cancer, hematological toxicity of radiation therapy for bone metastasis, DNA damage response in cancer metastasis, tumor endothelial cells and angiogenesis in cancer metastasis, apoptosis-induced compensatory proliferation in cancer, the potential of targeting apoptosis to overcome chemotherapy resistance, and features of metastatic Ewing sarcoma. This open access book is aimed primarily at clinicians and scientists, but many areas will also be of interest to the layperson.