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| 008 |
201006 ||| eng |
| 020 |
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|a 9789811544941
|
| 100 |
1 |
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|a Yu, Buwei
|e [editor]
|
| 245 |
0 |
0 |
|a Single-cell Sequencing and Methylation
|h Elektronische Ressource
|b Methods and Clinical Applications
|c edited by Buwei Yu, Jiaqiang Zhang, Yiming Zeng, Li Li, Xiangdong Wang
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| 250 |
|
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|a 1st ed. 2020
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| 260 |
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|a Singapore
|b Springer Nature Singapore
|c 2020, 2020
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| 300 |
|
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|a VIII, 247 p. 117 illus., 114 illus. in color
|b online resource
|
| 505 |
0 |
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|a Values of single-cell sequencing and methylation in molecular diagnosis and therapy -- Single-cell sequencing in human diseases -- Single-cell sequencing of T cell receptors: A perspective on the technological development and translational application -- DNA Methylation in pulmonary fibrosis -- Molecular regulation and clinical significance of caveolin-1 methylation in chronic lung diseases -- Research advances on DNA methylation in idiopathic pulmonary fibrosis -- DNA Methylation in Chronic Obstructive Pulmonary Disease -- Single cell sequencing: a new dimension in cancer diagnosis -- The Role of Methylation in the CpG Island of the ARHI Promoter Region in Cancers -- Clinical Significance of P16 Gene Methylation in Lung Cancer -- Application of single-cell RNA sequencing in pancreatic cancer and the endocrine pancreas -- Single Cell Sequencing in GU Malignancies -- PI3K Isoform-Selective Inhibitors in Cancer -- Single cell RNA sequencing in human disease: Renal, pancreatic, and viral diseases -- Single-cell sequencing in human genital infections -- PI3kinase Inhibitors in Thrombosis and Cardiovascular Disease -- Use of single-cell microfluidic technology towards therapeutic antibody discovery from single B cells
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| 653 |
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|a Bioinformatics
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| 653 |
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|a Medicine / Research
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| 653 |
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|a Biology / Research
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| 653 |
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|a Cancer
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| 653 |
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|a Biomedical Research
|
| 653 |
|
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|a Cancer Biology
|
| 700 |
1 |
|
|a Zhang, Jiaqiang
|e [editor]
|
| 700 |
1 |
|
|a Zeng, Yiming
|e [editor]
|
| 700 |
1 |
|
|a Li, Li
|e [editor]
|
| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
|
| 989 |
|
|
|b Springer
|a Springer eBooks 2005-
|
| 490 |
0 |
|
|a Advances in Experimental Medicine and Biology
|
| 028 |
5 |
0 |
|a 10.1007/978-981-15-4494-1
|
| 856 |
4 |
0 |
|u https://doi.org/10.1007/978-981-15-4494-1?nosfx=y
|x Verlag
|3 Volltext
|
| 082 |
0 |
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|a 610.72
|
| 520 |
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|a With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients
|