Single-cell Sequencing and Methylation Methods and Clinical Applications

With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a...

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Bibliographic Details
Other Authors: Yu, Buwei (Editor), Zhang, Jiaqiang (Editor), Zeng, Yiming (Editor), Li, Li (Editor)
Format: eBook
Language:English
Published: Singapore Springer Nature Singapore 2020, 2020
Edition:1st ed. 2020
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Description
Summary:With the rapid development of biotechnologies, single-cell sequencing has become an important tool for understanding the molecular mechanisms of diseases, defining cellular heterogeneities and characteristics, and identifying intercellular communications and single-cell-based biomarkers. Providing a clear overview of the clinical applications, the book presents state-of-the-art information on immune cell function, cancer progression, infection, and inflammation gained from single-cell DNA or RNA sequencing. Furthermore, it explores the role of target gene methylation in the pathogenesis of diseases, with a focus on respiratory cancer, infection and chronic diseases. As such it is a valuable resource for clinical researchers and physicians, allowing them to refresh their knowledge and improve early diagnosis and therapy for patients
Physical Description:VIII, 247 p. 117 illus., 114 illus. in color online resource
ISBN:9789811544941