DNA Replication, Recombination, and Repair Molecular Mechanisms and Pathology
This book is a comprehensive review of the detailed molecular mechanisms of and functional crosstalk among the replication, recombination, and repair of DNA (collectively called the "3Rs") and the related processes, with special consciousness of their biological and clinical consequences....
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Tokyo
Springer Japan
2016, 2016
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| Edition: | 1st ed. 2016 |
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Part 1 DNA Replication
- 1 Molecular Mechanism of DNA Replication
- 2 Characteristics of Metazoan DNA Replication Origins
- 3 DNA Replication Timing: Temporal and Spatial Regulation of Eukaryotic DNA Replication
- Part 2 DNA Recombination
- 4 Mechanism of Homologous Recombination
- 5 Regulation of Recombination by Chromatin
- 6 Homologous Recombination During Meiosis
- Part 3 DNA Repair
- 7 DNA Damage Recognition and Repair in Mammalian Global Genome Nucleotide Excision Repair
- 8 The Fanconi Anemia Pathway and Interstrand Crosslink Repair
- 9 The Crossroads of Ubiquitination and DNA Repair: A Structural Perspective
- Part 4 Genome Instability and Mutagenesis
- 10 Genome Instability of Repetitive Sequence: Lesson From the Ribosomal RNA Gene Repeat
- 11 Translesion DNA Synthesis and Damage Tolerance Pathways
- 12 Mismatch Repair
- 13 Non-Homologous End-Joining
- Part 5 Chromosome Dynamics and Functions
- 14 Centromeric Chromatin and Kinetochore Assembly in Vertebrate Cells
- 15 CST Complex and Telomere Maintenance
- Part 6 Cell Cycle and Checkpoints
- 16 Signaling of DNA Replication Stress Through the ATR Checkpoint
- 17 Spindle Assembly Checkpoint: Its Control and Aberration
- 18 Molecular Insights Into the Regulation of Apoptosis and Cellular Senescence and Their Implications for Cancer
- Part 7 Interplay with Transcription and Epigenetic Regulation
- 19 DNA Replication and Histone M odification
- 20 Establishment and Maintenance of DNA Methylation
- 21 Active DNA Demethylation in Development, Human Disease, and Cancer
- BM Index