DNA Repair

DNA is the central repository of genetic information in the cell, yet it is under constant attack by chemical mutagens, radiation and other processes. Cells therefore put a great deal of resources into repairing any damage to this precious store. Mechanisms of DNA repair vary greatly in their level...

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Corporate Author: SpringerLink (Online service)
Other Authors: Eckstein, Fritz (Editor), Lilley, David M.J. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1998, 1998
Edition:1st ed. 1998
Series:Nucleic Acids and Molecular Biology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Summary:DNA is the central repository of genetic information in the cell, yet it is under constant attack by chemical mutagens, radiation and other processes. Cells therefore put a great deal of resources into repairing any damage to this precious store. Mechanisms of DNA repair vary greatly in their level of complexity, from specific reversal mechanisms that involve a single protein, to sequential pathways that require many enzymes. But at the heart of all these mechanisms lie proteins that recognize damage to DNA, raising important questions about how damaged DNA may be distinguished. These recognition processes are now finally yielding their secrets to structural analysis. This volume focuses on DNA repair, with an emphasis on structural data where available
Physical Description:XI, 317 p. 19 illus. in color online resource
ISBN:9783642487705