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| LEADER |
02044nmm a2200265 u 4500 |
| 001 |
EB001082806 |
| 003 |
EBX01000000000000000842213 |
| 005 |
00000000000000.0 |
| 007 |
cr||||||||||||||||||||| |
| 008 |
151019 ||| eng |
| 100 |
1 |
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|a Clark, Mike
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| 245 |
0 |
0 |
|a Antibody engineering of Fc effector functions
|h Elektronische Ressource
|c Mike Clark
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| 246 |
3 |
1 |
|a Monoclonal antibodies as therapeutic agents
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| 260 |
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|a London
|b Henry Stewart Talks
|c 2007, 2007
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| 300 |
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|a 1 online resource (1 streaming video file (57 min.)
|b color, sound)
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| 505 |
0 |
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|a IgG structure and modes of action -- Human IgG Fc receptors -- Structural interactions -- Engineering strategy -- Selection of subclasses and effector functions -- Manipulation of functions -- Case study: FMAIT -- Design and engineering of inhibitory Fc mutants -- Functional properties -- Complement mediated lysis -- FcR binding -- Monocyte activation -- ADCC -- Clinical volunteer study -- Activatory mutations -- Enhanced binding to FcR -- Increased ADCC -- Possible applications
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| 653 |
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|a Antibodies, Monoclonal / therapeutic use
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| 653 |
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|a Receptors, Fc
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
|
| 989 |
|
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|b HST
|a Henry Stewart Talks
|
| 490 |
0 |
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|a Monoclonal antibodies as therapeutic agents : fundamentals, therapeutic applications and latest advances
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| 500 |
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|a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+
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| 856 |
4 |
2 |
|u https://hstalks.com/bs/p/30
|3 Series
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| 856 |
4 |
0 |
|u https://hstalks.com/bs/582
|x Verlag
|z Streaming video file
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| 082 |
0 |
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|a 570
|