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100 1 |a Field, Hugh J. 
245 0 0 |a Herpes simplex virus and varicella-zoster virus Helicase-Primase inhibitors  |h Elektronische Ressource  |c Hugh J. Field 
260 |a London  |b Henry Stewart Talks  |c 2011, 2011 
300 |a 1 online resource (1 streaming video file (35 min.)  |b color, sound) 
505 0 |a Herpesvirus infections in man -- Diseases caused by alphaherpesvirus, HSV and VZV -- Immunocompromised hosts -- Infection, latency and reactivation -- Morphology of herpesvirus virion -- Productive replication cycle -- The herpesvirus genome -- HSV and VZV antiviral therapy -- Nucleoside analogue therapy -- Historical prospective -- Genes coding for proteins targeted by antivirals -- Inhibitors of DNA synthesis -- A new target -- HSV helicase-primase complex -- Clinical potential of Helicase primase inhibitors (HPIs) -- Studying HPI in vivo -- Antiviral efficacy -- Dose response -- The effects of HPI on HSV latency -- The development of HPI antiviral drug resistance -- HPI resistant mutants growth and pathogenicity 
653 |a DNA Primase / antagonists & inhibitors 
653 |a DNA Helicases / antagonists & inhibitors 
653 |a Herpesvirus 3, Human / drug effects 
653 |a Antiviral agents 
653 |a Herpes Simplex / drug effects 
653 |a Herpes simplex virus / Effect of drugs on 
653 |a Herpesvirus diseases 
653 |a Antiviral Agents / pharmacology 
041 0 7 |a eng  |2 ISO 639-2 
989 |b HST  |a Henry Stewart Talks 
490 0 |a Antivirals : latest developments and future progress 
500 |a Animated audio-visual presentation with synchronized narration. - Title from title frames. - Mode of access: World Wide Web. - System requirements: Browser compatibility: updated Mozilla Firefox, Google Chrome, Safari or Internet Explorer 8+. Browser settings: enable JavaScript, enable cookies from the Henry Stewart Talks site. Required Desktop Browser plugins & viewers: Updated Adobe Flash Player & Adobe Acrobat Reader. Mobile device & operating system versions: Android v4.0+, iPhone 4+ (iOS v6.x+), iPad 2+ (iOS v6.x+), BlackBerry OS v7.0+, Windows Phone v6.5.1+ 
856 4 0 |u https://hstalks.com/bs/2074  |x Verlag  |z Streaming video file 
856 4 2 |u https://hstalks.com/bs/p/613  |3 Series 
082 0 |a 570