Comparative effectiveness of treatments to prevent fractures in men and women with low bone density or osteoporosis

This Comparative Effectiveness Review (CER) compares the benefits in fracture reduction and the harms from adverse events (AE) among and within the various classes of treatment for low bone density. Our outcomes of interest for measuring benefits are vertebral, non-vertebral, hip, and radial fractur...

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Main Author: MacLean, Catherine H.
Corporate Authors: United States Agency for Healthcare Research and Quality, Southern California Evidence-Based Practice Center/RAND.
Other Authors: Alexander, Alicia
Format: eBook
Language:English
Published: [Rockville, MD Agency for Healthcare Research and Quality 2007, 2007]
Series:Comparative effectiveness review
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Summary:This Comparative Effectiveness Review (CER) compares the benefits in fracture reduction and the harms from adverse events (AE) among and within the various classes of treatment for low bone density. Our outcomes of interest for measuring benefits are vertebral, non-vertebral, hip, and radial fractures. The studies collect vertebral fracture outcomes in one of two ways. In some studies, all participants undergo radiography at pre-determined intervals. Other studies use clinical criteria, i.e. whether a fracture has been diagnosed by a clinician during the time interval. Trials that radiograph all participants will by nature detect more fractures. However the higher detection rate will apply to both treatment and placebo groups. Thus, the relative differences found should be similar that found in studies that use clinical criteria
Item Description:Title from PDF t.p. (viewed Aug. 30, 2011). - "December 2007.". - "Contract no. 290-02-0003."
Physical Description:1 online resource (1 PDF file (1 v. (various pagings) ill.)