Drug Toxicity in Embryonic Development I Advances in Understanding Mechanisms of Birth Defects: Morphogenesis and Processes at Risk
Having received the invitation from Springer-Verlag to produce a volume on drug-induced birth defects for the Handbook of Experimental Pharmacology, we asked ourselves what new approach could we offer that would capture the state of the science and bring a new synthesis of the information on this to...
| Main Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
1997, 1997
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| Edition: | 1st ed. 1997 |
| Series: | Handbook of Experimental Pharmacology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- 1 Introduction
- Section I: Recent Advances in Understanding Normal Development at the Biochemical and Molecular Level
- 2 Cardiac Morphogenesis: Formation and Septation of the Primary Heart Tube
- 3 Vertebrate Limb Development
- 4 Axial Skeleton
- 5 Molecular Mechanisms Regulating the Early Development of the Vertebrate Nervous System
- 6 Genetic Control of Kidney Morphogenesis
- 7 Palate
- Section II: Common Biochemical, Metabolic, and Physiological Mechanisms of Abnormal Development
- 8 Cell Death
- 9 Cellular Responses to Stress
- 10 Cell-Cell Interactions
- 11 Growth Factor Disturbance
- 12 Targeted Gene Disruptions as Models of Abnormal Development
- 13 Nucleotide Pool Imbalance
- 14 Interference with Embryonic Intermediary Metabolism
- 15 Alterations in Folate Metabolism as a Possible Mechanism of Embryotoxicity
- 16 Prostaglandin Metabolism
- 17 Reactive Intermediates
- 18 Hypoxia and Altered Redox Status in Embryotoxicity
- 19 Altered Embryonic pH
- 20 Maternal Physiological Disruption