Drug Toxicity in Embryonic Development I Advances in Understanding Mechanisms of Birth Defects: Morphogenesis and Processes at Risk

The prevention of birth defects in the human populations caused by exogenous chemicals is a goal of both primary care providers, drug developers, experimental teratologists, and risk assessors. This two-volume work provides a state-of- the-science assessment of how embryos accomplish the feat of mor...

Full description

Main Author: Kavlock, Robert J.
Corporate Author: SpringerLink (Online service)
Other Authors: Daston, George P. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1997, 1997
Series:Handbook of Experimental Pharmacology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Summary:The prevention of birth defects in the human populations caused by exogenous chemicals is a goal of both primary care providers, drug developers, experimental teratologists, and risk assessors. This two-volume work provides a state-of- the-science assessment of how embryos accomplish the feat of morphogenesis at the molecular and cellular level, the key biochemical processes that drive morphogenesis and which are thus at risk to disruption, and the mechanisms of action by which known human teratogens exert their unwanted effects. These volumes provide the first comprehensive compilation of material focused on the understanding of the mechanism of action of chemicals which cause birth defects. It will prove a valuable reference work for clinicians, health councilors, teratologists, developmental biologists and risk assessors
Physical Description:XXVIII, 610p. 75 illus., 1 illus. in color online resource
ISBN:9783642604454