Protein Degradation in Health and Disease
Protein degradation has been identified as a centerpiece of regulation of cell functions. Not surprisingly, its deregulation is implied in almost any pathological condition. This book describes how aged proteins are eliminated during cell metabolism, how cell proliferation is regulated by protein de...
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| Format: | eBook |
| Language: | English |
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Berlin, Heidelberg
Springer Berlin Heidelberg
2002, 2002
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| Edition: | 1st ed. 2002 |
| Series: | Progress in Molecular and Subcellular Biology
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| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Roles of SCF and VHL Ubiquitin Ligases in Regulation of Cell Growth
- Aging of Proteins and the Proteasome
- Protein Degradation in the Aging Organism
- Protein Degradation in Alzheimer’s Disease and Aging of the Brain
- Protein Degradation in Human Disease
- The 26S Proteasome
- Proteasome Inhibitors