Cover Image
Read Now

Protein Degradation in Health and Disease

Protein degradation has been identified as a centerpiece of regulation of cell functions. Not surprisingly, its deregulation is implied in almost any pathological condition. This book describes how aged proteins are eliminated during cell metabolism, how cell proliferation is regulated by protein de...

Full description

Bibliographic Details
Other Authors: Reboud-Ravaux, Michele (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 2002, 2002
Edition:1st ed. 2002
Series:Progress in Molecular and Subcellular Biology
Subjects:
Cell Biology
Cytology
Cancer
Biochemistry
Cancer Biology
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
LEADER 02032nmm a2200313 u 4500
001 EB000664906
003 EBX01000000000000000517988
005 00000000000000.0
007 cr|||||||||||||||||||||
008 140122 ||| eng
020 |a 9783642563737 
100 1 |a Reboud-Ravaux, Michele  |e [editor] 
245 0 0 |a Protein Degradation in Health and Disease  |h Elektronische Ressource  |c edited by Michele Reboud-Ravaux 
250 |a 1st ed. 2002 
260 |a Berlin, Heidelberg  |b Springer Berlin Heidelberg  |c 2002, 2002 
300 |a X, 130 p  |b online resource 
505 0 |a Roles of SCF and VHL Ubiquitin Ligases in Regulation of Cell Growth -- Aging of Proteins and the Proteasome -- Protein Degradation in the Aging Organism -- Protein Degradation in Alzheimer’s Disease and Aging of the Brain -- Protein Degradation in Human Disease -- The 26S Proteasome -- Proteasome Inhibitors 
653 |a Cell Biology 
653 |a Cytology 
653 |a Cancer 
653 |a Biochemistry 
653 |a Cancer Biology 
041 0 7 |a eng  |2 ISO 639-2 
989 |b SBA  |a Springer Book Archives -2004 
490 0 |a Progress in Molecular and Subcellular Biology 
028 5 0 |a 10.1007/978-3-642-56373-7 
856 4 0 |u https://doi.org/10.1007/978-3-642-56373-7?nosfx=y  |x Verlag  |3 Volltext 
082 0 |a 571.6 
520 |a Protein degradation has been identified as a centerpiece of regulation of cell functions. Not surprisingly, its deregulation is implied in almost any pathological condition. This book describes how aged proteins are eliminated during cell metabolism, how cell proliferation is regulated by protein degradation and how its deregulation can contribute to the development of cancer, how protein degradation is modified during normal and abnormal aging, in particular with regard to Alzheimer's disease and other degenerative diseases of the brain and central nervous system. Attempts aiming at correcting these pathologies by interfering with deviations of the normal pathway of protein degradation are also treated 

Similar Items