Tumor Biomarker Discovery : Methods and Protocols

Through a variety of mechanisms, cancer cells provide the biomarker material that can lead to their own detection, which then grants clinicians the opportunity for non-invasive body fluid and tissue analysis able to indicate the presence of tumors or the level of tumor burden. In Tumor Biomarker Dis...

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Corporate Author: SpringerLink (Online service)
Other Authors: Tainsky, Michael A. (Editor)
Format: eBook
Published: Totowa, NJ Humana Press 2009, 2009
Edition:1st ed. 2009
Series:Methods in Molecular Biology
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Identification of Tumor-Associated Antigens as Diagnostic and Predictive Biomarkers in Cancer
  • Autoantibodies Against Cancer Antigens
  • Discovery of Antibody Biomarkers Using Protein Microarrays of Tumor Antigens Cloned in High Throughput
  • Analysis of Glycans on Serum Proteins Using Antibody Microarrays
  • Glycoproteomic Analysis by Two-Dimensional Electrophoresis
  • All-Liquid Separations, Protein Microarrays, and Mass Spectrometry to Interrogate Serum Proteomes: An Application to Serum Glycoproteomics
  • Reverse-Phase Protein Microarrays for Theranostics and Patient Tailored Therapy
  • Serum Proteomics Using Mass Spectrometry
  • Hormones as Biomarkers: Practical Guide to Utilizing Luminex Technologies for Biomarker Research
  • High-Throughput Analysis of Serum Antigens Using Sandwich ELISAs on Microarrays
  • Tissue Microarrays as a Tool in the Discovery and Validation of Tumor Markers
  • Quantitative, Fluorescence-Based In-Situ Assessment of Protein Expression
  • Tumor Marker Discovery by Expression Profiling RNA from Formalin Fixed Paraffin Embedded Tissues
  • High-Throughput Mutation Screening Using a Single Amplification Condition
  • DNA Sequencing of Cancer-Related Genes for Biomarker Discovery
  • Analysis of Loss of Heterozygosity in Circulating DNA
  • Pharmacogenomics
  • Study Designs in Genetic Epidemiology
  • Developing Classifiers for the Detection of Cancer Using Multi-Analytes
  • Metabolomics of Cancer
  • MRI and MRS of Human Brain Tumors
  • Magnetic Resonance Spectroscopy of Living Tissues