1 “...While three poor-quality analytic validity studies showed that technological advances can improve...”

2 “... confounders, and use of study designs complicated by recall bias. Results from the observational literature...”

3

4

5 “..., combined with six additional comparative studies evaluating the incremental value of receipt of spirometry...”

6 “... no studies designed to assess the adverse effects of dietary counseling and none of the included healthful...”

7 “... no studies designed to assess the adverse effects of dietary counseling and none of the included healthful...”

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9

10 “... specifically recruiting participants from vascular laboratories for screening accuracy studies and treatment...”

11 “... specifically recruiting participants from vascular laboratories for screening accuracy studies and treatment...”

12 “... studied as screening tests in more than one study. AChEIs, memantine, complex caregiver interventions...”

13 “... studied as screening tests in more than one study. AChEIs, memantine, complex caregiver interventions...”

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15

16 “... to understand the study design biases as well as limitations in information and data quality). To develop...”

17 “... to understand the study design biases as well as limitations in information and data quality). To develop...”

18 “... Trials (CENTRAL) from January 1, 2008 to June 2, 2017. STUDY SELECTION: We screened 453 abstracts and 34...”

19 “... Trials (CENTRAL) from January 1, 2008 to June 2, 2017. STUDY SELECTION: We screened 453 abstracts and 34...”

20 “... factors on patient health outcomes. The best available indirect evidence is mainly limited to studies...”