Environmental cleaning for the prevention of healthcare-associated infections

Future research should examine and compare newly emerging strategies, such as peracetic acid, hydrogen peroxide wipes, enhanced coatings, and microfiber cloths as cleaning strategies, and adenosine triphosphate and ultraviolet light technologies as monitoring strategies. Patient colonization and inf...

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Bibliographic Details
Main Author: Leas, Brian F.
Corporate Authors: United States Agency for Healthcare Research and Quality, ECRI Institute-Penn Medicine Evidence-based Practice Center, Effective Health Care Program (U.S.)
Format: eBook
Language:English
Published: Rockville, MD Agency for Healthcare Research and Quality [2015], 2015
Series:Technical brief
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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100 1 |a Leas, Brian F. 
245 0 0 |a Environmental cleaning for the prevention of healthcare-associated infections  |h Elektronische Ressource  |c prepared for Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by ECRI Institute--Penn Medicine Evidence-Based Practice Center, Plymouth Meeting, PA ; investigators, Brian F. Leas, Nancy Sullivan, Jennifer H. Han, David A. Pegues, Janice L. Kaczmarek, Craig A. Umscheid 
260 |a Rockville, MD  |b Agency for Healthcare Research and Quality  |c [2015], 2015 
300 |a 1 PDF file (various pagings)  |b illustrations 
505 0 |a Includes bibliographical references 
710 2 |a United States  |b Agency for Healthcare Research and Quality 
710 2 |a ECRI Institute-Penn Medicine Evidence-based Practice Center 
710 2 |a Effective Health Care Program (U.S.) 
041 0 7 |a eng  |2 ISO 639-2 
989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a Technical brief 
500 |a Title from PDF title page. - "August 2015." 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK311016  |3 Volltext 
082 0 |a 576 
520 |a Future research should examine and compare newly emerging strategies, such as peracetic acid, hydrogen peroxide wipes, enhanced coatings, and microfiber cloths as cleaning strategies, and adenosine triphosphate and ultraviolet light technologies as monitoring strategies. Patient colonization and infection rates should be included as outcomes when possible. Other challenges to be addressed include identification of surfaces posing the greatest risk of pathogen transmission, developing standard thresholds for defining cleanliness, and using methods to adjust for confounders such as hand-hygiene practices when examining the impact of disinfection modalities 
520 |a Additionally, 12 Key Informants were interviewed, representing environmental services management, hospital infection control, and clinical infectious diseases. FINDINGS: Eighty studies were included. Forty-nine studies examined cleaning modalities, including chemical agents, self-disinfecting surfaces, and no-touch technologies. Fourteen studies evaluated monitoring strategies, including visual inspection, microbiological cultures, assays, and ultraviolet light. Seventeen studies addressed challenges or facilitators to implementation. Sixty-five studies used nonrandomized concurrent or historical controls. The outcome of surface contamination was reported in 57 studies; infection rates were reported in 25. CONCLUSIONS: Comparative-effectiveness studies directly comparing disinfection modalities and monitoring strategies are limited.  
520 |a BACKGROUND: The cleaning of hard surfaces in hospital rooms is essential for reducing the risk of healthcare-associated infections. Many methods are available for cleaning and monitoring cleanliness, but their comparative effectiveness is not well understood. PURPOSE: This Technical Brief summarizes the evidence base addressing environmental cleaning of high-touch surfaces in hospital rooms and highlights future research directions. METHODS: A systematic search for published and gray literature since 1990 was performed using PubMed, EMBASE, CINAHL, the Cochrane Library, and other resources. Clinical studies examining the cleaning and disinfection of high-touch surfaces in adult inpatient hospital rooms were included. Primary outcomes of interest were patient infection, colonization, or surface contamination with Clostridium difficile, methicillin-resistant Staphylococcus aureus, or vancomycin-resistant enterococci.