Systematic reviews of complex multicomponent health care interventions

OBJECTIVE: The purpose of this report is to outline approaches to address the challenges of conducting systematic reviews of complex multicomponent health care interventions. METHODS: We performed a literature scan and conducted semi-structured interviews with international experts who conduct resea...

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Bibliographic Details
Main Author: Guise, Jeanne-Marie
Corporate Authors: United States Agency for Healthcare Research and Quality, Scientific Resource Center (Portland, Or.)
Format: eBook
Language:English
Published: Rockville, MD Agency for Healthcare Research and Quality 2014, March 2014
Series:Research white paper
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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100 1 |a Guise, Jeanne-Marie 
245 0 0 |a Systematic reviews of complex multicomponent health care interventions  |h Elektronische Ressource  |c prepared for, Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services ; prepared by, Scientific Resource Center ; investigators, Jeanne-Marie Guise, Christine Chang, Meera Viswanathan, Susan Glick, Jonathan Treadwell, Craig A. Umscheid, Evelyn Whitlock, Rochelle Fu, Elise Berliner, Robin Paynter, Johanna Anderson, Pua Motu'apuaka, Tom Trikalinos 
260 |a Rockville, MD  |b Agency for Healthcare Research and Quality  |c 2014, March 2014 
300 |a 1 PDF file (various pagings) 
505 0 |a Includes bibliographical references 
710 2 |a United States  |b Agency for Healthcare Research and Quality 
710 2 |a Scientific Resource Center (Portland, Or.) 
041 0 7 |a eng  |2 ISO 639-2 
989 |b NCBI  |a National Center for Biotechnology Information 
490 0 |a Research white paper 
500 |a Title from PDF title page 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK194846  |3 Volltext 
082 0 |a 610 
520 |a OBJECTIVE: The purpose of this report is to outline approaches to address the challenges of conducting systematic reviews of complex multicomponent health care interventions. METHODS: We performed a literature scan and conducted semi-structured interviews with international experts who conduct research or systematic reviews of complex multicomponent interventions, or organizational leaders who implement complex multicomponent interventions in health care. RESULTS: Challenges identified include: a lack of consistent terminology for such interventions (e.g., complex; multicomponent; multidimensional; multifactorial); a wide range of approaches used to frame the review, from grouping interventions by common features to using more theoretical approaches; decisions regarding whether and how to quantitatively analyze the interventions, from more holistic to individual component analytic approaches; and incomplete and inconsistent reporting in primary and secondary studies of those elements critical to understanding the success and impact of such interventions, such as the methods used to implement the intervention, and the context in which it is implemented. CONCLUSIONS: We provided a framework to understand the spectrum of conceptual and analytic approaches and an initial list of critical reporting elements for primary and secondary studies of multicomponent interventions. This information will help reviewers understand the options and tradeoffs available for such reviews