Patient-Derived Xenografts Methods and Protocols
This detailed volume explores the dynamic landscape of patient-derived xenograft (PDX) generation and applications. After a few chapters examining the evolution of PDXs, tracing their roots and contextualizing their significance in the broader narrative of cancer research, the book continues with me...
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| Format: | eBook |
| Language: | English |
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New York, NY
Humana
2024, 2024
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| Edition: | 1st ed. 2024 |
| Series: | Methods in Molecular Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Patient-Derived Xenografts: Historical Evolution, Immunocompromised Host Models, and Translational Significance
- Patient-Derived Xenograft Models in Cancer Research: Methodology, Applications, and Future Prospects
- Patient-Derived Xenografts: A Valuable Preclinical Model for Drug Development and Biomarker Discovery
- Patient-Derived Xenograft Models for Leukemias
- Patient-Derived Orthotopic Xenograft Models for High-Grade Pediatric Brain Cancers
- Generation of Orthotopic and Subcutaneous Patient-Derived Xenograft Models from Diverse Clinical Tissue Samples of Pediatric Extracranial Solid Tumors
- Development of Orthotopic Patient-Derived Xenograft Models of Pediatric Intracranial Tumors
- A Humanized Patient-Derived Xenograft Model for Pancreatic Cancer
- Development and Expansion of Patient-Derived Xenografts for Endometrial Cancer
- A Multiplexed Approach to Assess Small Cell Lung Cancer Subtype Heterogeneity in Primary and Patient-Derived Tumor Samples
- Generation of Metastatic Cholangiocarcinoma Patient-Derived Xenograft Models
- Patient-Derived Xenograft Models for Translational Prostate Cancer Research and Drug Development
- Patient-Derived Xenograft Models for Ovarian Cancer
- Orthotopic MC-38 Allograft as a Robust Preclinical Model of Colorectal Carcinoma
- Assessing Protein Expression in Patient-Derived Xenografts Using Western Blotting
- Analysis of Protein Interactions in Patient-Derived Xenografts Using Immunoprecipitation
- A Semi-Automated Proteomics and Phosphoproteomics Protocol for the Identification of Novel Therapeutic Targets and Predictive Biomarkers in In Vivo Xenograft Models of Pediatric Cancers