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Current Insights on Lipid-Based Nanosystems 2023

Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions, and liposomes, have been extensively studied to improve drug delivery through different administration routes. The main advantages linked to these...

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Bibliographic Details
Main Author: Silva, Ana Catarina
Other Authors: Moreira, João, Sousa Lobo, José Manuel
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
Subjects:
Central Composite Design
Jak-inhibitor
Ocular Bioavailability
Mannosylation
Solid Lipid Nanoparticles (slns)
N/a
Co-encapsulation
Sln
Gentiopicroside
Acute Toxicity
Skin Permeation
In Vivo Pharmacokinetics
Nose-to-brain
Isoniazid
Antioxidants
Large-scale Production
Empty Lipid Nanoparticles
Cisplatin
Glaucoma
Sirna Delivery
Self-nanoemulsion Drug Delivery System
Transepidermal Delivery
Phospholipid Complex
Niosomes
Drug Release Profile
Technology: General Issues / Bicssc
Nlc
Oral Bioavailability
Anticancer
In Vivo Assays
Xenobiotics
Exosomal Delivery
Design Of Experiment
Neurodegenerative Diseases
Mtt Assay
Porcine Mucous Membrane
Pharmacokinetics
Biodistribution
Ionizable Lipids
Surfactant
In Vivo Imaging
Breast Cancer
Synergism
Antidepressant
Intranasal Administration
Surface Modification
Solid Lipid Nanoparticles
Personalized Therapy
Trypanosoma Cruzi
Nanostructured Lipid Carriers
Exosome
In Vitro
Mucoadhesion
Baricitinib
Reactogenicity
Breast Cancer Cell
Stability
Diabetes
Quality By Design
Lipid
Chagas Disease
Permeation
Nanocarriers
Gefitinib
Levosulpiride
Lipid Nps
Mifepristone
Perillyl Acid
Bimatoprost
Liposomes
Ophthalmic Tissues
Lipid Nanoparticles
Marine Bio-waste
Bioactive Compounds
Drug Loading
Gene Silencing
Bioavailability
Plumbagin
Histopathological Toxicity
Het-cam Test
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions, and liposomes, have been extensively studied to improve drug delivery through different administration routes. The main advantages linked to these systems are the ability to protect, transport, and control the release of lipophilic and hydrophilic molecules (either small molecular weight or macromolecules); the use of generally recognized as safe (GRAS) excipients that minimize the toxicity of the formulations; and the possibility to modulate pharmacokinetics and enable the site-specific delivery of encapsulated payloads. In addition, the versatility of lipid-based nanosystems has been further demonstrated through the delivery of vaccines, protection of cosmetic actives, or improvement in the moisturizing properties of cosmetic formulations. Currently, lipid-based nanosystems are well established, and there are already different commercially approved formulations for different human disorders. This success has actually paved the way to diversifying the pipeline of development, upon addressing unmet medical needs for several indications, such as cancer; neurological disorders; and autoimmune, genetic, and infectious diseases. This Special Issue aims to update readers on the latest research on lipid-based nanosystems, both at the preclinical and clinical levels.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (340 p.)
ISBN:books978-3-0365-9805-5
9783036598062
9783036598055

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