Gene Expression and Regulation in Mammalian Cells Transcription Toward the Establishment of Novel Therapeutics

Sixty years after the "central dogma," great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specifi...

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Bibliographic Details
Main Author: Uchiumi, Fumiaki
Format: eBook
Language:English
Published: IntechOpen 2018
Subjects:
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:Sixty years after the "central dogma," great achievements have been developed in molecular biology. We have also learned the important functions of noncoding RNAs and epigenetic regulations. More importantly, whole genome sequencing and transcriptome analyses enabled us to diagnose specific diseases. This book is not only intended for students and researchers working in laboratory but also physicians and pharmacists. This volume consists of 14 chapters, divided into 4 parts. Each chapter is written by experts investigating biological stresses, epigenetic regulation, and functions of transcription factors in human diseases. All articles presented in this volume by excellent investigators provide new insights into the studies in transcriptional control in mammalian cells and will inspire us to develop or establish novel therapeutics against human diseases.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/3.0/
Physical Description:1 electronic resource (372 p.)
ISBN:9789535138686
9789535140993
intechopen.74045
9789535138679