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01888nma a2200325 u 4500 |
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240202 ||| eng |
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|a 9789535128380
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|a 9789535128373
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|a 9789535154624
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|a 62743
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100 |
1 |
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|a Antonio Morales-Gonzalez, Jose
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245 |
0 |
0 |
|a The Transcription Factor Nrf2
|h Elektronische Ressource
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260 |
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|b IntechOpen
|c 2016
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300 |
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|a 1 electronic resource (210 p.)
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653 |
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|a Proteins
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653 |
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|a Molecular biology / bicssc
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700 |
1 |
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|a Morales-Gonzalez, Angel
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700 |
1 |
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|a Osiris Madrigal-Santillan, Eduardo
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700 |
1 |
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|a Antonio Morales-Gonzalez, Jose
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041 |
0 |
7 |
|a eng
|2 ISO 639-2
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989 |
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|b DOAB
|a Directory of Open Access Books
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500 |
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|a Creative Commons (cc), https://creativecommons.org/licenses/by/3.0/
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024 |
8 |
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|a 10.5772/62743
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856 |
4 |
0 |
|u https://mts.intechopen.com/storage/books/5407/authors_book/authors_book.pdf
|7 0
|x Verlag
|3 Volltext
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856 |
4 |
2 |
|u https://directory.doabooks.org/handle/20.500.12854/129317
|z DOAB: description of the publication
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520 |
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|a Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.
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