The Transcription Factor Nrf2

Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. The...

Full description

Bibliographic Details
Main Author: Antonio Morales-Gonzalez, Jose
Other Authors: Morales-Gonzalez, Angel, Osiris Madrigal-Santillan, Eduardo
Format: eBook
Language:English
Published: IntechOpen 2016
Subjects:
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
LEADER 01888nma a2200325 u 4500
001 EB002195530
003 EBX01000000000000001332995
005 00000000000000.0
007 cr|||||||||||||||||||||
008 240202 ||| eng
020 |a 9789535128380 
020 |a 9789535128373 
020 |a 9789535154624 
020 |a 62743 
100 1 |a Antonio Morales-Gonzalez, Jose 
245 0 0 |a The Transcription Factor Nrf2  |h Elektronische Ressource 
260 |b IntechOpen  |c 2016 
300 |a 1 electronic resource (210 p.) 
653 |a Proteins 
653 |a Molecular biology / bicssc 
700 1 |a Morales-Gonzalez, Angel 
700 1 |a Osiris Madrigal-Santillan, Eduardo 
700 1 |a Antonio Morales-Gonzalez, Jose 
041 0 7 |a eng  |2 ISO 639-2 
989 |b DOAB  |a Directory of Open Access Books 
500 |a Creative Commons (cc), https://creativecommons.org/licenses/by/3.0/ 
024 8 |a 10.5772/62743 
856 4 0 |u https://mts.intechopen.com/storage/books/5407/authors_book/authors_book.pdf  |7 0  |x Verlag  |3 Volltext 
856 4 2 |u https://directory.doabooks.org/handle/20.500.12854/129317  |z DOAB: description of the publication 
520 |a Due to that at present, the majority of diseases are associated with alterations in oxidative stress and inflammatory processes, and in that Nrf-2 is a modulator of these processes; knowing how this transcriptional factor functions and is regulated opens a therapeutic window to diverse diseases. Therefore, the efforts of various investigation groups are centered on finding activators and/or inhibitors of Nrf-2 to prevent or control diverse diseases, for example, cancer, where it would be important to regulate Nrf-2 in order for it to activate apoptosis pathways in cancerogenous cells, or in neurodegenerative diseases where cell death is predominant, it would be important for Nrf-2 to activate antiapoptotic pathways.