Teratogenicity Testing Methods and Protocols
This fully updated volume collects laboratory techniques and tests to assess the risks to embryo-fetal development from drug exposure during early developmental stages. Beginning with a section detailing basic principles of teratogenicity, the book continues with application of in vitro models for t...
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| Format: | eBook |
| Language: | English |
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New York, NY
Humana
2024, 2024
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| Edition: | 2nd ed. 2024 |
| Series: | Methods in Molecular Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Updating an Overview of Teratology
- Guidelines on Development Toxicity Tests: Brief Insights
- Development Features on the Selection of Animal Models for Teratogenic Testing
- Virus as Teratogenic Agents
- The Future of the Teratogenicity Testing
- The First Steps on AOPs' Concepts, Development, and Applications in Teratology
- Machine Learning to Predict Teratogenicity: Theory and Practice
- Human Pluripotent Stem Cell-Based Assays to Predict Developmental Toxicity
- Developmental Toxicity Using the Rat Whole Embryo Culture
- A Modified Murine Embryonic Stem Cell Test for Evaluating the Teratogenic Effects of Drugs
- Teratogenic Effects of Drugs on Primary Lymphocytes Assessed by Flow Cytometry
- Assessment of the Teratogenic Effect of Drugs on the Chicken Embryo
- Daphnia magna as a Model Organism to Predict the Teratogenic Effect of Different Compounds
- Caenorhabditis elegans as an In Vivo Model Organism to Elucidate Teratogenic Effects
- Enduring Ethanol-Induced Behavioral Alterations in Caenorhabditis elegans after Developmental Lead Exposure
- Exploration of Teratogenic and Genotoxic Effects on Model Organism Drosophila melanogaster
- Ecotoxicological Assessment of Seaweed-Based Crop Biostimulant on Earthworm Eudrilus eugeniae Kinb
- Evaluation of the Ecotoxicology of Seaweed-Based Biopesticide Used in Combat of the Polyphagous Pest Using Eudrilus eugeniae Kinb
- Biochemical Studies to Understand Teratogenicity and Lethality Outcomes in Modified-FETAX
- Bioinformatics Methods for Transcriptome Analysis on Teratogenesis Testing
- Angiogenesis Assay for Live and Fixed Zebrafish Larvae
- High-Resolution Respirometry for the Assessment of Teratogenic Chemicals
- A Stereological Approach to Quantify Immunohistochemical Staining in Zebrafish Larvae
- Whole-Mount Immunohistochemical and Immunofluorescence Assays in Zebrafish Embryos
- Assessment of Developmental Neurotoxicity Using Semi-Automatic Behavior Analysis System for Zebrafish
- Behavioral Profiling of Zebrafish (Danio rerio) Larvae: Activity, Anxiety, Avoidance, and Startle Response
- Alcian Blue Staining for Chondrocranium Development in Zebrafish
- Protocol of Geometric Morphometrics for Teratogenicity Testing
- Biochemical Markers for Liver Injury in Zebrafish Larvae
- Cortisol Quantification for Assessing Stress-Induced Changes in Zebrafish Larvae
- Metabolomic Fingerprint Assay in Zebrafish Embryos
- Alkaline Comet Assay to Assess Genotoxicity in Zebrafish Larvae
- A Chromogenic Quantification of Protein Expression in Zebrafish Larvae
- Confocal Microscopy Technique in Teratogenicity Testing Using Zebrafish (Danio rerio) Embryos as Model
- Whole-Mount RNA In Situ Hybridization of Zebrafish Embryos
- Quantitative Real-Time PCR Method to Evaluate Gene Expression in Zebrafish Embryos
- Microarray Analysis to Determine Gene Expression Changes in Zebrafish Embryos
- Cell-Free DNA and Next-GenerationSequencing for Prenatal Diagnosis