| Summary: | This guide provides a rationale for synthesizing evidence from health policy and systems research (HPSR) to support health policy-making and health systems strengthening. It introduces key challenges in synthesizing HPSR evidence and provides guidance on addressing these issues, including suggestions for framing a synthesis question, assessing context-sensitive evidence, understanding complexity, addressing health equity, selecting the appropriate synthesis approaches for HPSR questions, presenting the evidence and making sense of the findings for health policy and systems decision-making. This Guide examines various synthesis methods - quantitative, qualitative and mixed methods - and provides practical guidance to engage decision-makers in evidence synthesis, enhance the policy relevance of syntheses and foster the uptake of review findings in policy and practice
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