Mechanisms and Emerging Therapies in Tremor Disorders

Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that infl...

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Bibliographic Details
Other Authors: Grimaldi, Giuliana (Editor), Manto, Mario (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2023, 2023
Edition:2nd ed. 2023
Series:Contemporary Clinical Neuroscience
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Description
Summary:Tremor is intimately linked to the numerous interactions of the central and peripheral nervous system components tuning motor control, from the cerebral cortex to the peripheral effectors. Activities of central generators, reflex loop delays, inertia, stiffness, and damping are all factors that influence the features of tremor. This completely updated new edition discusses the pathophysiology of tremor, including membrane mechanisms and rodent models, the advances in genetics, and the musculoskeletal models pertinent to body oscillations. The main forms of tremor encountered during clinical practice are considered, taking into account neuroimaging aspects. The book covers recent advances in methodologies and techniques of assessment and provides practical information for daily management. This new edition is informed by the guidelines of the Tremor Task Force of the International Parkinson and Movement Disorders Society. New chapters include Classification of Tremors, Medically Induced Tremors, Resting State fMRI, and Gabaergic Pathways. In addition to pharmacological treatments, neurosurgical approaches such as deep brain stimulation (DBS) and thalamotomy are discussed. Emerging techniques under development are also introduced
Physical Description:X, 558 p. 86 illus., 59 illus. in color online resource
ISBN:9783031261282