| Summary: | The ATSDR toxicological profile succinctly characterizes the toxicology and adverse health effects information for the toxic substance described therein. Each peer-reviewed profile identifies and reviews the key literature that describes a substance's toxicological properties. Mirex and chlordecone are structurally similar highly-chlorinated derivatives of cyclopentadiene. The only structural difference between mirex and chlordecone is that mirex has two bridgehead chlorine atoms where chlordecone has a carbonyl oxygen atom. Mirex was commercially introduced in the United State sin 1959 for use in pesticide formulations and as an industrial fire retardant. In the 1960s, mirex was commonly used to control fire ants in southern States. Mirex was banned for use in the United States in1978, except for use on pineapples until stocks on hand were exhausted. Chlordecone was mainly registered for use in the United States to control banana root borer, although it was also used to control other pests. All registered products containing chlordecone were effectively canceled in 1978
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