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230811 ||| eng |
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|a books978-3-0365-7145-4
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|a 9783036571447
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|a 9783036571454
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|a Burrow, Heather
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| 245 |
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|a Application of Genetics and Genomics in Livestock Production
|h Elektronische Ressource
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| 260 |
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|a Basel
|b MDPI - Multidisciplinary Digital Publishing Institute
|c 2023
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| 300 |
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|a 1 electronic resource (222 p.)
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|a beef cattle
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|a development
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|a DNA pooling
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|a single-step
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|a degradation
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|a phenotypes
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|a response
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|a inflammation
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|a adaptive introgression
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|a OTUD7A
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|a Technology, Engineering, Agriculture, Industrial processes / bicssc
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| 653 |
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|a breed conservation
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| 653 |
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|a n/a
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|a genetic evaluation
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|a capacity-building
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|a fertility
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|a linkage disequilibrium
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|a breeding strategies
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|a genomic relationship
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|a CCBE1
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|a genomic evaluation
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| 653 |
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|a ssGBLUP
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|a HOXC8
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|a imputation
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|a genomic selection
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|a index selection
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| 653 |
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|a ssGTBLUP
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|a resistance to environmental stressors
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| 653 |
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|a productive traits
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| 653 |
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|a genetic groups
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|a chicken
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|a tropical environments
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|a sheep and goats
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| 653 |
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|a nonalcoholic fatty liver disease
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|a metafounder
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|a positive selection
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|a cashmere goats
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|a immune
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| 653 |
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|a genotype by environment
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| 653 |
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|a heritability
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| 653 |
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|a Biology, life sciences / bicssc
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| 653 |
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|a smallholder farmers
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|a value of genomic information
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|a within-breed selection
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|a Holstein
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|a DPCs
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|a cattle
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|a parentage
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|a RSPO1
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|a sequencing
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|a runs of homozygosity
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|a quantitative trait loci
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|a haplotype
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|a crossbreeding
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|a strategy
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|a genomic prediction
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|a circRNAs
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|a goose
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|a implementation
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|a selection index
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| 653 |
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|a reproduction
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| 653 |
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|a reference populations
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| 653 |
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|a high density genotyping
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| 653 |
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|a beef and dairy cattle
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| 653 |
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|a reference population
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| 653 |
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|a variance components
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| 653 |
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|a causal variants
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| 653 |
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|a transcriptomic analysis
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| 653 |
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|a Research and information: general / bicssc
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| 653 |
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|a bursa of Fabricius
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| 700 |
1 |
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|a Goddard, Michael
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| 700 |
1 |
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|a Burrow, Heather
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| 700 |
1 |
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|a Goddard, Michael
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b DOAB
|a Directory of Open Access Books
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| 500 |
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|a Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
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| 024 |
8 |
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|a 10.3390/books978-3-0365-7145-4
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| 856 |
4 |
2 |
|u https://directory.doabooks.org/handle/20.500.12854/112436
|z DOAB: description of the publication
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| 856 |
4 |
0 |
|u https://www.mdpi.com/books/pdfview/book/7547
|7 0
|x Verlag
|3 Volltext
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| 082 |
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|a 363
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|a 000
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|a 630
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|a 610
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|a 333
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|a 600
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|a 620
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|a The delivery of genome sequences for most livestock species over the past 10-15 years has generated the potential to revolutionise livestock production globally, by providing farmers with the ability to match individual animals to rapidly changing climates, production systems and markets. Initially, technologies such as marker-assisted selection, functional genomics, gene expression, transcriptomics, proteomics and metabolomics were hailed as technologies with the greatest promise of delivering on that potential. To date, however, their potential for the delivery of practical solutions for livestock farmers is still to be realised, though they do provide supportive evidence of value to other approaches. Gene editing using tools such as CRISPR-Cas9 also show strong promise, but face regulatory hurdles before practical applications can be delivered for use by farmers. The technology that has had the greatest impact to date is genomic selection. This year marks 20 years since genomic selection was developed by Meuwissen, Hayes and Goddard (Genetics, 2001, 157: 1819-1829) and genomic selection has been successfully applied in livestock, plants and even human health applications. However, genomic selection also faces ongoing limitations around lack of essential phenotypes, particularly for expensive or difficult-to-measure traits and possibly the need for faster/greater computational capacity. It is therefore timely to examine the impact of genomic technologies generally, and to identify successes and limitations that need to be overcome in order to achieve practical applications for livestock producers in future.
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