MPG.eBooks - Table of Contents: Genetics of chronic obstructive pulmonary disease (COPD)

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Bibliographic Details
Main Author:	Tobin, Martin J.
Format:	eBook
Language:	English
Published:	London Henry Stewart Talks 2023, 2023
Series:	Advances in chronic obstructive pulmonary disease (COPD) : new mechanisms, management strategies and treatments
Subjects:	Respiration Disorders / Genetics Genome-wide Association Study Drug Development Pulmonary Disease, Chronic Obstructive / Epidemiology Lungs / Diseases / Genetic Aspects Pulmonary Disease, Chronic Obstructive / Genetics Medical Genetics Lungs / Diseases, Obstructive Genetic Predisposition To Disease
Online Access:	https://hstalks.com/bs/5357 https://hstalks.com/bs/p/673
Collection:	Henry Stewart Talks - Collection details see MPG.ReNa

Table of Contents:

Contents: Routine use of genetic evidence in drug target discovery and validation
Genetically supported targets can double the success rate in clinical development
COPD has the highest prevalence of chronic respiratory diseases globally
SpiroMeta consortium: understanding the genetic determinants of COPD
Understanding the tractability of drug targets
Identification of statistically independent genetic associations (signals) for lung function
Use of phonome-wide association studies
DeepPheWAS: testing pathway-specific GRS to infer possible consequences of intervening in pathways underlying lung function