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230704 ||| eng |
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|a 9783031356315
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| 100 |
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|a Hussain, Afzal
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| 245 |
0 |
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|a Therapeutic Rhodium Complexes
|h Elektronische Ressource
|c by Afzal Hussain, Mohamed F. Alajmi, Mushtaq Ahmad Lone, Waseem A. Wani
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| 250 |
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|a 1st ed. 2023
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| 260 |
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|a Cham
|b Springer Nature Switzerland
|c 2023, 2023
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| 300 |
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|a XVII, 70 p. 61 illus., 2 illus. in color
|b online resource
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| 505 |
0 |
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|a Introduction: Metal Complexes as Therapeutic Agents -- Chemistry of Rhodium -- Therapeutic Potential of Rhodium Complexes -- Mechanism of Therapeutic Action of Rhodium Complexes -- Challenges and Future Outlooks of Research
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| 653 |
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|a Medicinal chemistry
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| 653 |
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|a Coordination Chemistry
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| 653 |
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|a Microclusters
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| 653 |
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|a Coordination compounds
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| 653 |
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|a Medicinal Chemistry
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| 653 |
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|a Bioinorganic Chemistry
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| 653 |
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|a Atomic and Molecular Clusters
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| 653 |
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|a Bioinorganic chemistry
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| 700 |
1 |
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|a Alajmi, Mohamed F.
|e [author]
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| 700 |
1 |
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|a Lone, Mushtaq Ahmad
|e [author]
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| 700 |
1 |
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|a Wani, Waseem A.
|e [author]
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 490 |
0 |
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|a SpringerBriefs in Molecular Science
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| 028 |
5 |
0 |
|a 10.1007/978-3-031-35631-5
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| 856 |
4 |
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|u https://doi.org/10.1007/978-3-031-35631-5?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 572.51
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| 520 |
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|a This book describes the emergence and recent advances in the design and development of rhodium complexes as therapeutic agents. Different classes of anticancer rhodium complexes with particular emphasis on ligands containing nitrogen-oxygen donor atoms are presented. Anticancer rhodium complexes of N-heterocyclic carbenes are described, while half-sandwich, heterobimetallic, and multinuclear rhodium complexes are discussed. Therapeutic applications of rhodium complexes beyond cancer such as antibacterial agents or antiviral agents are also analyzed, among others. Their mechanism of action is overviewed in detail, and the authors thoroughly comment on the challenges and future outlooks of research in the development of rhodium metallodrugs. This title highlights the important research carried out in the development of therapeutic rhodium complexes and is of great interest to graduates and researchers working in the area of rhodium-based therapeutic drugs
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