Stem Cell-Based Neural Model Systems for Brain Disorders
This detailed volume presents validated and well-adapted procedures involving humanized and/or stem cell-based neural model systems that have proven helpful in better understanding the essential brain functions involved in the pathogenesis of brain disorders. The book explores the generation of mult...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Humana
2023, 2023
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| Edition: | 1st ed. 2023 |
| Series: | Methods in Molecular Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Generation of Cerebral Cortical Neurons from Human Pluripotent Stem Cells in 3D Culture
- Generation of Homogeneous Populations of Cortical Interneurons from Human Pluripotent Stem Cells
- Generation and Co-Culture of Cortical Glutamatergic and GABAergic Induced Neuronal Cells
- Transcription Factor-Directed Dopaminergic Neuron Differentiation from Human Pluripotent Stem Cells
- Directed Differentiation of Human iPSCs into Microglia-Like Cells Using Defined Transcription Factors
- The Generation and Functional Characterization of Human Microglia-Like Cells Derived from iPS and Embryonic Stem Cells
- Modeling Cellular Crosstalk of Neuroinflammation Axis by Tri-Cultures of iPSC-Derived Human Microglia, Astrocytes, and Neurons
- Generation of Oligodendrocytes from Human Pluripotent and Embryonic Stem Cells
- Characterizing the Neuron-Glial Interactions by the Co-Cultures of Human iPSC-Derived Oligodendroglia and Neurons
- Defined Differentiation of Human Pluripotent Stem Cells to Brain Microvascular Endothelial-Like Cells for Modeling the Blood-Brain Barrier
- Modeling the Blood-Brain Barrier Using Human Induced Pluripotent Stem Cells
- A Three-Dimensional Primary Cortical Culture System Compatible with Transgenic Disease Models, Virally-Mediated Fluorescence, and Live Microscopy
- Method to Generate Dorsal Forebrain Brain Organoids from Human Pluripotent Stem Cells
- A 3D Bioengineered Neural Tissue Model Generated from Human iPSC-Derived Neural Precursor Cells
- FACS-Based Sequencing Approach to Evaluate Cell Type to Genotype Associations Using Cerebral Organoids
- Dynamic Measurement of Endosome-Lysosome Fusion in Neurons Using High-Content Imaging
- Live-Imaging Detection of Multivesicular Body-Plasma Membrane Fusion and Exosome Release in Cultured Primary Neurons
- Assays of Monitoring and Measuring Autophagic Flux for iPSC-Derived Human Neurons and Other Brain Cell Types
- Measuring Neuronal Network Activity Using Human Induced Neuronal Cells
- A Simple Ca2+-Imaging Approach of Network-Activity Analyses for Human Neurons
- Whole Cell Patch Clamp Electrophysiology in Human Neuronal Cells
- Assaying Chemical Long-Term Potentiation in Human iPSC-Derived Neuronal Networks