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Hypoxia in Cancer: Significance and Impact on Cancer Therapy

This book reviews the central role of hypoxia in cancer initiation and progression. It discusses the mechanisms of hypoxia in chemoresistance, radioresistance, angiogenesis, vasculogenesis, metastasis, metabolic, and genomic instability. It also explores the potential of hypoxia in the diagnosis and...

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Bibliographic Details
Other Authors: Mukherjee, Sukhes (Editor), Kanwar, Jagat Rakesh (Editor)
Format: eBook
Language:English
Published: Singapore Springer Nature Singapore 2023, 2023
Edition:1st ed. 2023
Subjects:
Tumors / Immunological Aspects
Cancers
Tumour Immunology
Cancer
Cancer Therapy
Cancer / Treatment
Cancer Biology
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Chapter 1. Hypoxia and its Biological Implications for Cancer Therapy
  • Chapter 2. Hypoxia's function in cancer
  • Chapter 3. Role of Hypoxia and Reactive Oxygen Species in cancer biology
  • Chapter 4. Hypoxic tumor microenvironment: driver for cancer progression
  • Chapter 5. Hypoxia and Senescence: Role of Oxygen in Modulation of Tumor Suppression
  • Chapter 6. Hypoxia Regulated Gene Expression and Metastasis
  • Chapter 7. piRNA based cancer therapy in hypoxic tumor
  • Chapter 8. MicroRNA Signatures of Tumor Hypoxia
  • Chapter 9. Hypoxia and the Metastatic Cascade
  • Chapter 10. Hypoxia and Extra Cellular Matrix-major drivers of tumor Metastasis
  • Chapter 11. Role of Hypoxia in Cancer Therapy – Introduction
  • Chapter 12. Hypoxic regulation of telomerase gene expression in cancer
  • Chapter 13. CRISPR/Cas9-editing-based modeling of tumor hypoxia
  • Chapter 14. Tumor-on-a-chip: Microfluidic models for Hypoxic tumor microenvironment
  • Chapter 15. Imaging the Hypoxic Tumor microenvironment in cancer models
  • Chapter 16. Hypoxia-targeting drugs as new cancer chemotherapy agents Hypoxia-targeting drugs as new cancer chemotherapy agents - Molecular Insights
  • Chapter 17. Identification of Hypoxia targeting drugs in the tumor microenvironment and prodrug Strategies for Targeting Tumor Hypoxia
  • Chapter 18. Hypoxia Induced Apoptosis in Cancer Development
  • Chapter 19. Hypoxia in drug resistance and radioresistance

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