Exploring psychedelics and entactogens as treatments for psychiatric disorders proceedings of a workshop

Psychiatric illnesses -- such as major depressive disorder, anxiety disorder, substance use disorder, and posttraumatic stress disorder (PTSD) -- are widely prevalent and represent a substantial health burden worldwide. Yet, conventional medications for mental illnesses often fail to provide relief...

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Bibliographic Details
Main Author: Bain, Lisa J.
Corporate Authors: National Academies of Sciences, Engineering, and Medicine (U.S.) Forum on Neuroscience and Nervous System Disorders, Exploring Psychedelics and Entactogens as Treatments for Psychiatric Disorders (Workshop) (2022, Online)
Other Authors: Matney, Chanel ([rapporteur]), Norris, Sheena M. Posey ([rapporteur]), Stroud, Clare ([rapporteur])
Format: eBook
Language:English
Published: Washington, DC National Academies Press 2022, [2022]
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:Psychiatric illnesses -- such as major depressive disorder, anxiety disorder, substance use disorder, and posttraumatic stress disorder (PTSD) -- are widely prevalent and represent a substantial health burden worldwide. Yet, conventional medications for mental illnesses often fail to provide relief to patients' disruptive and disabling symptoms. Existing and emerging evidence that psychedelics (e.g., LSD and psilocybin) and entactogens (e.g., MDMA) may be useful as tools to alleviate mental illness has sparked a renaissance of interest by investigators, clinicians, drug developers, and patient advocates in recent years. While promising data on therapeutic efficacy has energized research and development, resolving the mechanisms of action will be important for optimizing the efficacy and safety of these medicines. Further, evaluating the effect of psychedelics and entactogens on mood and behavior comes with unique challenges still in need of resolution. These include unresolved questions relating to blinding, placebo and nocebo effects, and the impact of psychosocial contexts. In response to this renewed interest, the National Academies of Sciences, Engineering, and Medicine's Forum on Neuroscience and Nervous System Disorders convened a workshop on March 29-30, 2022. The workshop brought together a diverse group of stakeholders to explore the use of psychedelics and entactogens as treatments for psychiatric disorders. This Proceedings of a Workshop summarizes the presentations and discussions of the workshop
Physical Description:1 PDF file (97 pages) illustrations
ISBN:0309691370
9780309691376