Opium consumption

This volume of the IARC Monographs provides an evaluation of the carcinogenicity of opium consumption. Opium is a highly addictive narcotic drug that has been used for centuries for medicinal and non-medicinal purposes. It has analgesic, hypnotic, antitussive, gastrointestinal, and cognitive effects...

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Bibliographic Details
Corporate Authors: IARC Working Group on the Identification of Carcinogenic Hazards to Humans, International Agency for Research and Cancer
Format: eBook
Language:English
Published: Lyon, France International Agency for Research on Cancer 2021, 2021
Series:IARC monographs on the identification of carcinogenic hazards to humans
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Description
Summary:This volume of the IARC Monographs provides an evaluation of the carcinogenicity of opium consumption. Opium is a highly addictive narcotic drug that has been used for centuries for medicinal and non-medicinal purposes. It has analgesic, hypnotic, antitussive, gastrointestinal, and cognitive effects. Produced from the juice (latex) of the unripe seedpod of the poppy plant (Papaver somniferum), opium has a complex chemical composition consisting of at least 25 alkaloids (e.g. morphine, codeine, thebaine) and other substances. There are several forms of opium (raw or crude opium, dross, refined opium or opium sap), all of which can be smoked or ingested. Opium derivatives such as morphine, codeine, and heroin were not considered in the present monograph. Although opium production and distribution are controlled internationally, opium is produced illicitly in some 50 countries worldwide, with more than 80% coming from Afghanistan. The world's largest per capita consumers of raw or minimally processed opium are the Islamic Republic of Iran, Afghanistan, and Pakistan. In 2018, there were an estimated 5 million users of illicit opium worldwide. After reviewing epidemiological evidence, animal bioassays, and mechanistic data to assess the carcinogenic hazard to humans of opium consumption, the IARC Monographs Working Group concluded that opium consumption is carcinogenic to humans
Item Description:"This publication represents the views and expert opinions of the IARC Working Group on the Identification of Carcinogenic Hazards to Humans, which met remotely, 11-20 September 2020."
Physical Description:1 PDF file (iv 253 pages) illustrations
ISBN:9789283201939
9789283201656