Viruses and Nuclear Egress
This Special Issue of Viruses focuses on the topic of viruses and nuclear egress. Nuclear egress is a fascinating process by which herpesvirus nucleocapsids make their way from the nuclear interior to the cytoplasm. As nuclear egress and the viral proteins that orchestrate it differ from host proces...
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| Format: | eBook |
| Language: | English |
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MDPI - Multidisciplinary Digital Publishing Institute
2022
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| Collection: | Directory of Open Access Books - Collection details see MPG.ReNa |
| Summary: | This Special Issue of Viruses focuses on the topic of viruses and nuclear egress. Nuclear egress is a fascinating process by which herpesvirus nucleocapsids make their way from the nuclear interior to the cytoplasm. As nuclear egress and the viral proteins that orchestrate it differ from host processes and proteins in important ways, there is interest in targeting antiviral therapies to disrupt this process. Indeed, the recently approved drug maribavir acts in large part by inhibiting a step of nuclear egress. The Special Issue includes five reviews-three on nuclear egress of two alphaherpesviruses, herpes simplex virus and pseudorabies virus; one on a betaherpevirus, human cytomegalovirus; and one on a gammaherpesvirus, Epstein-Barr virus-and five research papers-two on alphaherpesviruses and three on human cytomegalovirus. |
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| Item Description: | Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/ |
| Physical Description: | 1 electronic resource (182 p.) |
| ISBN: | 9783036556963 books978-3-0365-5695-6 9783036556956 |