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230102 ||| eng |
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|a 9783031179334
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100 |
1 |
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|a Bokros, Jack
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245 |
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|a Heart of Carbon
|h Elektronische Ressource
|b The Story Behind the Pursuit of the Perfect Mechanical Heart Valve
|c by Jack Bokros
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250 |
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|a 1st ed. 2023
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260 |
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|a Cham
|b Springer International Publishing
|c 2023, 2023
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300 |
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|a XLI, 268 p. 164 illus., 30 illus. in color
|b online resource
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505 |
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|a Timeline of Events/Overview -- Nuclear Foundations -- Origin and Characterization of Medical Carbons -- Gott’s Early Experience – A Lesson in Serendipity -- First Carbon Heart Valve Replacement -- First All-Carbon Mitral Valve Replacement -- Monoleaflet Tilting Disc Valves -- First Bileaflet Valve: St Jude Medical Start-up -- General Atomic Medical Products Division -- Carbomedics Gets Acquainted With Intermedics -- Carbomedics Moves to Austin Texas -- The Hemex Venture -- The St Jude Medical Litigation -- Broadening the Horizon -- Two Valves for China -- Negotiating Chinese Joint Venture -- European Company Buys Intermedics -- Medtronic Venture: Carbon Implants -- The Agreement -- Medtronic Clinical Trial -- Medical Carbon Research Institute/On-X Life Technologies -- Valve Design -- Clinical Trials -- Design Validation -- Studies Concurrent With FDA Trials -- Understanding Cardiac Blood Flow -- Investigating the Viability of Bioprostheses -- On-X Valve Implantability -- Selling the On-X Valve -- The Video -- Cryolife Buys On-X Life Technologies -- Mervyn Williams' South African Trial Results -- Summary and Reflections
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653 |
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|a Fluid mechanics
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653 |
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|a Engineering Fluid Dynamics
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653 |
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|a Cardiology
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653 |
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|a Biomedical engineering
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653 |
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|a Heart—Surgery
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653 |
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|a Cardiovascular system
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653 |
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|a Physiology
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653 |
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|a Biomedical Engineering and Bioengineering
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653 |
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|a Cardiovascular Physiology
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653 |
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|a Cardiac Surgery
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041 |
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7 |
|a eng
|2 ISO 639-2
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989 |
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|b Springer
|a Springer eBooks 2005-
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028 |
5 |
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|a 10.1007/978-3-031-17933-4
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856 |
4 |
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|u https://doi.org/10.1007/978-3-031-17933-4?nosfx=y
|x Verlag
|3 Volltext
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082 |
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|a 610.28
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520 |
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|a This book offers a historical account of the development of the On-X carbon mechanical heart valve, discussing the steps involved in developing the materials, and describes how the design of the valve has evolved over the years. It explores both the scientific and corporate problems researchers have encountered over the years in the journey of making a mechanical heart valve. The chapters provide a detailed description of the design of the mechanical leaflet-based prosthetic valve, with a particular focus on blood flow characteristics. This book includes an overview of the state-of-the-art in the chemistry and physics of carbon, and compiles the advances in carbon-based technology and its applications in cardiac and thoracic surgery. This is an ideal book for bioengineers working on the chemistry and physics of carbon, and other professionals involved with cardiac and thoracic surgery
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