Timing of introduction of complementary foods and beverages and bone health a systematic review

BACKGROUND: 1. Complementary feeding is the process that starts when human milk or infant formula is complemented by other foods and beverages, beginning during infancy and typically continuing to 24 months of age.2. This systematic review was conducted by the Nutrition Evidence Systematic Review (N...

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Bibliographic Details
Main Author: Obbagy, Julie E.
Corporate Author: Center for Nutrition Policy and Promotion (U.S.) Nutrition Evidence Systematic Review
Format: eBook
Language:English
Published: Alexandria, VA U.S. Department of Agriculture, Food and Nutrition Service, Center for Nutrition Policy and Promotion, Nutrition Evidence Systematic Review April 2019, 2019
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
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100 1 |a Obbagy, Julie E. 
245 0 0 |a Timing of introduction of complementary foods and beverages and bone health  |h Elektronische Ressource  |b a systematic review  |c Julie E. Obbagy, Laural K. English, Tricia L. Psota, Perrine Nadaud, Kirsten Johns, Yat Ping Wong, Nancy Terry, Nancy F. Butte, Kathryn G. Dewey, David M. Fleischer, Mary Kay Fox, Frank R. Greer, Nancy F. Krebs, Kelley S. Scanlon, Kellie O. Casavale, Joanne M. Spahn, Eve Stoody 
260 |a Alexandria, VA  |b U.S. Department of Agriculture, Food and Nutrition Service, Center for Nutrition Policy and Promotion, Nutrition Evidence Systematic Review  |c April 2019, 2019 
300 |a 1 PDF file (70 pages)  |b illustrations 
505 0 |a Includes bibliographical references 
710 2 |a Center for Nutrition Policy and Promotion (U.S.)  |b Nutrition Evidence Systematic Review 
041 0 7 |a eng  |2 ISO 639-2 
989 |b NCBI  |a National Center for Biotechnology Information 
500 |a "This systematic review has also been published in the American Journal of Clinical Nutrition, 2019;109(7):872S-878S" --PDF title page verso 
856 4 0 |u https://www.ncbi.nlm.nih.gov/books/NBK581989  |3 Volltext 
082 0 |a 610 
520 |a BACKGROUND: 1. Complementary feeding is the process that starts when human milk or infant formula is complemented by other foods and beverages, beginning during infancy and typically continuing to 24 months of age.2. This systematic review was conducted by the Nutrition Evidence Systematic Review (NESR) team as part of the U.S. Department of Agriculture and Department of Health and Human Services Pregnancy and Birth to 24 Months Project.3. The goal of this systematic review was to answer the following research question: What is the relationship between timing of introduction of complementary foods and beverages and bone health? CONCLUSION STATEMENT AND GRADES: 1. Insufficient evidence is available to draw conclusions about the relationship between the timing of introduction of complementary foods and beverages and bone health. Grade: [Grade Not Assignable] METHODS: 1.  
520 |a This systematic review was conducted by a team of staff from NESR in collaboration with a Technical Expert Collaborative.2. A literature search was conducted using 4 databases (CINAHL, Cochrane, Embase, and PubMed) to identify articles published from January 1980 to July 2016 that examined the age when complementary foods and beverages (CFB) were first introduced and bone health. CFB were defined as foods and beverages other than human milk or infant formula provided to an infant or young child. Bone health outcomes included bone, biomarkers of bone metabolism, and incidence and prevalence of osteoporosis, osteopenia, rickets, and fracture. A manual search was done to identify articles that may not have been included in the electronic databases searched. Articles were screened in a dual manner, independently by 2 NESR analysts, to determine which articles met predetermined criteria for inclusion.3. Data from each included article were extracted, risk of bias was assessed.  
520 |a The observational studies did not measure and/or account for a number confounding factors that could have impacted the relationship between timing of CFB introduction and bone health later in childhood.4. The ability to draw conclusions about the relationship between the timing of CFB introduction and bone health is limited by an overall lack of research, as well as heterogeneity in the three studies included in this systematic review with regards to methodology, subject populations, and results 
520 |a The body of evidence was qualitatively synthesized, a conclusion statement was developed and the strength of the evidence (grade) was assessed using pre-established criteria including evaluation of the internal validity/risk of bias, adequacy, consistency, impact, and generalizability of available evidence. Research recommendations were identified. SUMMARY OF EVIDENCE: 1. Three studies met the inclusion criteria for this systematic review, one randomized controlled trial, one prospective cohort study, and one case-control study.2. The randomized controlled trial included a small sample of infants fed only vitamin D fortified infant formula, and did not follow infants long enough to assess the impact of timing of introduction to CFB and bone health, as outcomes were assessed when infants were 26 weeks (wk) of age.3.