| Summary: | The eye has long been considered an immune privileged site. Blood and lymphatic vessels are excluded from the central light path that passes through the cornea and the lens, and limited to more peripheral regions of the eye. Yet, immune cells are required to maintain tissue homeostasis and mediate the reparative responses to injury and pathogenic insults. This webinar will focus on recent discoveries, which revealed that the lens, an avascular tissue in the anterior segment of the eye, plays an important role in activating, recruiting and regulating immune responses in the absence of an embedded vasculature. ... The evidence presented will all point to the lens, located in the center of the eye and interfacing with the anterior, equatorial and posterior compartments of the eye, as a previously unappreciated regulator of inflammation in the immune privileged eye that is key to maintaining its homeostasis
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