Summary: | Immune memory is seen in all vertebrates and presents as the ability to mount an enhanced response upon repeat encounter with a pathogen or antigen. Whilst some T cells patrol the blood, a unique subset called tissue-resident memory T (TRM) cells permanently exists within tissues of the body. TRM cells form a defensive barrier in the tissue where they can provide immediate local control of disease. The discovery of TRM cells and their role in local immunity has formed a new paradigm of how memory T cells confer immune protection, changing the way we think about designing new T cell vaccines. In this webinar, we will discuss the role of these key immune cells in providing protection against infection and cancer, as well as recent advances in tissue-resident memory T cell biology
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