The dynamic neuron a comprehensive survey of the neurochemical basis of synaptic plasticity
The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a...
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| Format: | eBook |
| Language: | English |
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Cambridge, Mass.
MIT Press
2002
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| Collection: | MIT Press eBook Archive - Collection details see MPG.ReNa |
| Summary: | The traditional model of synapses as fixed structures has been replaced by a dynamic one in which synapses are constantly being deleted and replaced. This book, written by a leading researcher on the neurochemistry of schizophrenia, integrates material from neuroscience and cell biology to provide a comprehensive account of our current knowledge of the neurochemical basis of synaptic plasticity. The book presents the evidence for synaptic plasticity, an account of the dendritic spine and the glutamate synapse with a focus on redox mechanisms, and the biochemical basis of the Hebbian synapse. It discusses the role of endocytosis, special proteins, and local protein synthesis. Additional topics include volume transmission, arachidonic acid signaling, hormonal modulation, and psychological stress. Finally, the book considers pharmacological and clinical implications of current research, particularly with reference to schizophrenia and Alzheimer's disease |
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| Item Description: | "A Bradford book." |
| Physical Description: | viii, 150 pages illustrations |
| ISBN: | 0585442592 0262283980 9780585442594 9780262283984 |