Leaders in Cardiovascular Research: A Special Issue Dedicated to Professor Adriana Gittenberger-De Groot

The arterial pole is one of the most complex parts of the heart both in development and disease. It involves the collaboration and orchestration of contributions from the first and second heart fields as well as the neural crest. The precursor cells differentiate into endocardial cushions and putati...

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Bibliographic Details
Main Author: Jongbloed, Monique
Other Authors: Poelmann, Robert
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
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653 |a endocardial cushions 
653 |a original leaflet 
653 |a sudden unexpected intrauterine death 
653 |a left aorta 
653 |a single coronary artery 
653 |a coronary artery anatomy 
653 |a signaling networks 
653 |a cartilage 
653 |a endocardial fibro-elastosis 
653 |a surgical 
653 |a arteria lusoria 
653 |a Tetralogy of Fallot 
653 |a aortic surgery 
653 |a epigenetics 
653 |a imaging 
653 |a arterial switch operation 
653 |a aorta 
653 |a dissection of ductus arteriosus 
653 |a cardiovascular pathogenesis 
653 |a rienhoff syndrome 
653 |a cleft palate 
653 |a ductus arteriosus 
653 |a Rac1 
653 |a valve 
653 |a asymptomatic 
653 |a transposition great arteries coronary anatomy 
653 |a homograft 
653 |a transforming growth factor beta-3 
653 |a superimposed tissue 
653 |a candidate genes 
653 |a cardiovascular disease 
653 |a cell polarity 
653 |a cardiovascular development 
653 |a cardiomyocyte 
653 |a coronary complications 
653 |a tunica media 
653 |a major cushion 
653 |a cell identity 
653 |a tracheal compression 
653 |a variations 
653 |a transposition of the great arteries 
653 |a proliferation 
653 |a lateral cushion 
653 |a coronary arteries 
653 |a Public health and preventive medicine / bicssc 
653 |a bicuspid aortic valve 
653 |a neointima 
653 |a cardiac progenitor cells 
653 |a congenital heart defects 
653 |a cardiac fields 
653 |a outflow tract septation 
653 |a genetics 
653 |a right sided aortic arch 
653 |a outflow tract 
653 |a transcriptome 
653 |a esophageal compression 
653 |a lineage tracing 
653 |a neural crest cell 
653 |a watchful waiting 
653 |a heart tube 
653 |a neural crest 
653 |a pulmonary trunk 
653 |a foramen of Panizza 
653 |a semilunar valves 
653 |a trabeculation 
653 |a acute aortic syndrome 
653 |a myofibroblasts 
653 |a congenital heart disease 
653 |a anomalous left subclavian artery 
653 |a Lipton classification 
653 |a postmortem histology 
653 |a progenitor specification 
653 |a cardiac development 
653 |a second heart field 
653 |a pharyngeal ectoderm 
653 |a free edge folding 
653 |a developmental biology 
653 |a right aorta 
653 |a aortic regurgitation 
653 |a pharyngeal arch artery 
653 |a remodeling 
653 |a aortic wall 
653 |a DNA methylation 
653 |a prenatal ultrasound 
653 |a compact myocardium 
653 |a loeys dietz syndrome-5 
653 |a discordant phenotype 
653 |a fetal aortic stenosis 
653 |a arrhythmogenic right ventricular dysplasia 
653 |a early surgery 
653 |a myxomatous degeneration 
653 |a aortic stenosis 
653 |a atrioventricular valve 
653 |a Leiden Convention coronary coding system 
653 |a aortic valve replacement 
653 |a Bentall 
653 |a pharyngeal arch arteries 
653 |a epicardium 
653 |a monozygotic twins 
653 |a coronary artery 
653 |a Kommerell's diverticulum 
653 |a arterial duct 
653 |a endocardium 
653 |a transcription factor AP-2α 
653 |a speckle tracking analysis 
653 |a cushion 
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520 |a The arterial pole is one of the most complex parts of the heart both in development and disease. It involves the collaboration and orchestration of contributions from the first and second heart fields as well as the neural crest. The precursor cells differentiate into endocardial cushions and putative cardiac valves, the myocardium, and epicardium of the heart, but also into the different layers of the main arterial vessels. These include not only the aorta and the pulmonary trunk but also the pulmonary and coronary arteries, and during development, the arterial duct. Many transcriptional and signaling networks act in timely concert to acquire the proper asymmetric development and function and pressure and flow dynamics. This is not only a human or even mammalian 'enterprise,' but is also taking place in so-called ancestral forms from fish to reptiles, including birds. In humans, it is small wonder that many clinical syndromes may arise when something in this complexity is amiss. This Special Issue of JCDD contains contributions focussed on the heart fields, congenital cardiac malformations and associated syndromes, with special emphasis on the cardiac outflow tract. The Issue is devoted to Prof. Dr. Adriana Gittenberger-de Groot, who dedicated her extensive career to research on cardiovascular development.