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220822 ||| eng |
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|a books978-3-0365-3082-6
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|a 9783036530833
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|a 9783036530826
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|a El Yazidi-Belkoura, Ikram
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|a O-GlcNAcylation and Cancer
|h Elektronische Ressource
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260 |
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|a Basel
|b MDPI - Multidisciplinary Digital Publishing Institute
|c 2022
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300 |
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|a 1 electronic resource (112 p.)
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653 |
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|a energy metabolism
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|a invasiveness
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|a EZH2
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|a SAM68
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|a transcription
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|a glucose
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|a epigenetics
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|a mitochondria
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|a O-GlcNAcase
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|a nutrition
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|a immune surveillance
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|a OGT
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|a O-GlcNAcylation
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|a O-GlcNAc transferase
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|a breast cancer
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|a cancer
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|a mOGT
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|a colon cancer
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|a O-GlcNAc
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|a lung adenocarcinoma
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|a cellular stress
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|a UNC5A
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|a Research and information: general / bicssc
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1 |
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|a Lefebvre, Tony
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1 |
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|a El Yazidi-Belkoura, Ikram
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|a Lefebvre, Tony
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041 |
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7 |
|a eng
|2 ISO 639-2
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989 |
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|b DOAB
|a Directory of Open Access Books
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500 |
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|a Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
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028 |
5 |
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|a 10.3390/books978-3-0365-3082-6
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856 |
4 |
2 |
|u https://directory.doabooks.org/handle/20.500.12854/78822
|z DOAB: description of the publication
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4 |
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|u https://www.mdpi.com/books/pdfview/book/4917
|7 0
|x Verlag
|3 Volltext
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|a 000
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|a 333
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|a This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.
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