O-GlcNAcylation and Cancer

This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcriptio...

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Bibliographic Details
Main Author: El Yazidi-Belkoura, Ikram
Other Authors: Lefebvre, Tony
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Ogt
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
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653 |a energy metabolism 
653 |a O-GlcNAc transferase 
653 |a breast cancer 
653 |a invasiveness 
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653 |a colon cancer 
653 |a transcription 
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653 |a epigenetics 
653 |a lung adenocarcinoma 
653 |a cellular stress 
653 |a O-GlcNAcase 
653 |a nutrition 
653 |a immune surveillance 
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653 |a UNC5A 
653 |a O-GlcNAcylation 
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520 |a This book gathers reviews and articles on the role of O-GlcNAcylation in cancer underlying the pharmacological targeting of the O-GlcNAcylation enzymes OGT and OGA as a promising anticancer strategy. Particular attention is paid to the involvement of O-GlcNAcylation in the regulation of transcription and as a link between nutrition and epigenetic dynamics or cellular energy metabolism. The role of O-GlcNAcylation in metastasis, immune responses, and resistance to chemotherapeutic agents is also discussed.