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Method Development and Applications for Reduced-Risk Products in Separation Science

In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and governmen...

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Bibliographic Details
Main Author: Aldeek, Fadi
Format: eBook
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Nicotine Extraction
Ends
Nicotine-related Impurities
Derivatization
Modern Oral Nicotine Products
Compliance Marker
N/a
Nicotine Degradation Products
Release Profile
2,4-dnph Derivatization
On!® Nicotine Pouches
Propylene Glycol
Aerosol
Product Characterizations
Formaldehyde
Nicotine Dissolution
Method Development
Nicotine
Gc-ms
Snus
Dissolution
Reduced-risk Products
Nicotine Degradants
Oral Tobacco Derived Nicotine (otdn) Pouches
Alkaloids
Research & Information: General / Bicssc
Non-targeted Analysis
Potentially Reduced-risk Products
Formaldehyde-containing Hemiacetal/acetal Adducts
E-liquid
Hphcs
Product Assessment
Smokeless Tobacco Product
Lc-hrms
Nicotine Pouches
Human Biomonitoring
Biomarker Of Exposure
Juul
Analytical Chemistry / Bicssc
Hphc
Urine
Chemical Characterization
"hidden Formaldehyde"
3-hydroxybenzo[a]pyrene
E-cigarette
Equivalence
Method Validation
Constituents
Validation
Nicotine Release
Lc-ms/ms
Chemistry / Bicssc
Electronic Cigarette
Online Access:
Collection: Directory of Open Access Books - Collection details see MPG.ReNa
Description
Summary:In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and government researchers are developing and validating analytical methods to extract, separate, identify, and quantitate a variety of analytes from these innovative tobacco products using a wide range of analytical techniques. These analytes include constituents such as nicotine, degradants and impurities, flavors, non-tobacco ingredients, HPHCs, and other currently unknown constituents. In this Special Issue, we received nine contributions that covered the latest analytical methods that have been developed and applied for the chemical characterization or exposure assessment to tobacco product constituents of innovative non-combustible products. This Special Issue is representative of the importance of analytical sciences research in characterizing innovative non-combustible products for guiding product design, determining relative product performance, ensuring consistency during the manufacturing process, informing toxicological risk assessment, and enabling regulatory reporting. The current advances in the development and applications of the analytical methods reported in this Special Issue can be used to inform the harm reduction potential of innovative non-combustible products for adult smokers.
Item Description:Creative Commons (cc), https://creativecommons.org/licenses/by/4.0/
Physical Description:1 electronic resource (154 p.)
ISBN:books978-3-0365-3638-5
9783036536378
9783036536385

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