Toll-like Receptors in Health and Disease
The current book is focussed on the Toll-like receptors (TLRs), which are the first pattern recognition receptors (PRRs) discovered in humans. For example, TLR4 was first recognized in humans in 1997 as a PRR recognizing the Gram-negative bacterial lipopolysaccharide (LPS). This discovery revolution...
| Other Authors: | |
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| Format: | eBook |
| Language: | English |
| Published: |
Cham
Springer International Publishing
2022, 2022
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| Edition: | 1st ed. 2022 |
| Series: | Handbook of Experimental Pharmacology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Intracellular TLRs (TLR3, TLR7, and TRL9) in host defense or TLRs in mast cells
- Toll-like receptors as drug targets in the intestinal epithelium
- Innate immune memory-priming, tolerance and exhaustion-in health and disease
- TLRs in brain immunity
- TLRs in cerebrovascular diseases
- TLRs in stem cells or progenitor cells
- TLRs in adaptive immunity
- Overview on TLRs in immunity
- TLR10 and its role in immunity