| Summary: | While there is evidence to suggest that mechanical bowel preparation should not be used in isolation, there is renewed interest in determining the value of adding oral antibiotics to the preoperative regimen for elective colorectal procedures. For instance, a recent retrospective database analysis has suggested that there may be an important role for the combination of mechanical bowel preparation and oral antibiotics in reducing postoperative surgical site infections in elective colorectal surgery. Thus, this report aims to review relevant evidence addressing the clinical effectiveness, cost-effectiveness, and evidence-based guidelines for the use of standard, parenteral antibiotic prophylaxis with or without mechanical bowel preparation versus intravenous plus oral antibiotic prophylaxis with or without mechanical bowel preparation for patients undergoing elective colorectal procedures
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