Chemical Biology and Drug Discovery

The focus of this textbook is on application, rather than pure knowledge transfer of the results of all chemical biological work (which would also be beyond the scope of a book). It gives the reader, through the specific selection of chemical-biological techniques and concepts, the necessary tools t...

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Bibliographic Details
Main Author: Schmidt, Marco F.
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 2022, 2022
Edition:1st ed. 2022
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Foreword
  • Introduction
  • Part I: Chemical Biology and Drug Development
  • Chemical Biology - a Holistic Science
  • Drug Development
  • From Genomics to Chemical Biology
  • Part II: DNA
  • DNA - blueprint of proteins
  • Genomic Variation
  • Gene Therapy and Genome Editing
  • Part III: RNA
  • RNA - information and function carrier
  • RNA Interference in Drug Development
  • Part IV: Proteins
  • Peptides & proteins
  • Proteins as drug targets
  • Chemical genomics - From target protein to drug
  • From target protein to macromolecular drug - Biologics
  • Chemical proteomics: From drug to target protein
  • Chemical genetics: validation of drug target by elucidation of signaling pathway
  • Chemical biology - Addressing new drug targets