Clinical trial design Bayesian and frequentist adaptive methods
There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practic...
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Hoboken, NJ
Wiley
2012
|
| Edition: | First edition |
| Series: | Wiley series in probability and statistics
|
| Subjects: | |
| Online Access: | |
| Collection: | Wiley Online Books - Collection details see MPG.ReNa |
| Summary: | There has been enormous interest and development in Bayesian adaptive designs, especially for early phases of clinical trials. However, for phase III trials, frequentist methods still play a dominant role through controlling type I and type II errors in the hypothesis testing framework. From practical perspectives, Clinical Trial Design: Bayesian and Frequentist Adaptive Methods provides comprehensive coverage of both Bayesian and frequentist approaches to all phases of clinical trial design. Before underpinning various adaptive methods, the book establishes an overview of the fundamentals of clinical trials as well as a comparison of Bayesian and frequentist statistics. |
|---|---|
| Physical Description: | xvii, 336 Seiten |
| ISBN: | 9781118183335 |